Synthetic and Antimicrobial Studies of Some new Chalcones of 3-Bromo-4-(p-tolyl sulphonamido) acetophenone

Eleven new chalcones have been sysnthesised by condensing 3-bromo-4-(p-tolyl sulphonamido) acetophenone with different aromatic aldehydes using the method or Rohrman et al. The antimicrobial activity of these chalcones has been tested by adopting “paper disc diffusion plate method”, against various...

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Main Authors: Miss Rashmi Jain, O. P. Chourasia, J. Tirumala Rao
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2004/810524
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author Miss Rashmi Jain
O. P. Chourasia
J. Tirumala Rao
author_facet Miss Rashmi Jain
O. P. Chourasia
J. Tirumala Rao
author_sort Miss Rashmi Jain
collection DOAJ
description Eleven new chalcones have been sysnthesised by condensing 3-bromo-4-(p-tolyl sulphonamido) acetophenone with different aromatic aldehydes using the method or Rohrman et al. The antimicrobial activity of these chalcones has been tested by adopting “paper disc diffusion plate method”, against various pathogenic fungi and bacteria. It has been found that the chalcones have considerable antifungal activity but less antibacterial activity. The results show that these chalcones may find use as antifungal agents.
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spelling doaj-art-25d19e017705458ab00a8ae956acfc362025-08-20T02:04:21ZengWileyE-Journal of Chemistry0973-49452090-98102004-01-011317818310.1155/2004/810524Synthetic and Antimicrobial Studies of Some new Chalcones of 3-Bromo-4-(p-tolyl sulphonamido) acetophenoneMiss Rashmi Jain0O. P. Chourasia1J. Tirumala Rao2Department of Chemistry Dr. H.S. Gour Vishwavidyalaya, Sagar (M.P.) 470 003, IndiaDepartment of Chemistry Dr. H.S. Gour Vishwavidyalaya, Sagar (M.P.) 470 003, IndiaDepartment of Chemistry Dr. H.S. Gour Vishwavidyalaya, Sagar (M.P.) 470 003, IndiaEleven new chalcones have been sysnthesised by condensing 3-bromo-4-(p-tolyl sulphonamido) acetophenone with different aromatic aldehydes using the method or Rohrman et al. The antimicrobial activity of these chalcones has been tested by adopting “paper disc diffusion plate method”, against various pathogenic fungi and bacteria. It has been found that the chalcones have considerable antifungal activity but less antibacterial activity. The results show that these chalcones may find use as antifungal agents.http://dx.doi.org/10.1155/2004/810524
spellingShingle Miss Rashmi Jain
O. P. Chourasia
J. Tirumala Rao
Synthetic and Antimicrobial Studies of Some new Chalcones of 3-Bromo-4-(p-tolyl sulphonamido) acetophenone
E-Journal of Chemistry
title Synthetic and Antimicrobial Studies of Some new Chalcones of 3-Bromo-4-(p-tolyl sulphonamido) acetophenone
title_full Synthetic and Antimicrobial Studies of Some new Chalcones of 3-Bromo-4-(p-tolyl sulphonamido) acetophenone
title_fullStr Synthetic and Antimicrobial Studies of Some new Chalcones of 3-Bromo-4-(p-tolyl sulphonamido) acetophenone
title_full_unstemmed Synthetic and Antimicrobial Studies of Some new Chalcones of 3-Bromo-4-(p-tolyl sulphonamido) acetophenone
title_short Synthetic and Antimicrobial Studies of Some new Chalcones of 3-Bromo-4-(p-tolyl sulphonamido) acetophenone
title_sort synthetic and antimicrobial studies of some new chalcones of 3 bromo 4 p tolyl sulphonamido acetophenone
url http://dx.doi.org/10.1155/2004/810524
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