Hepatoid Adenocarcinoma of the Urachus

Hepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microsco...

Full description

Saved in:
Bibliographic Details
Main Authors: Daniel Fernando Gallego, Carlos Muñoz, Carlos Andrés Jimenez, Edwin Carrascal
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2016/1871807
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850228569735692288
author Daniel Fernando Gallego
Carlos Muñoz
Carlos Andrés Jimenez
Edwin Carrascal
author_facet Daniel Fernando Gallego
Carlos Muñoz
Carlos Andrés Jimenez
Edwin Carrascal
author_sort Daniel Fernando Gallego
collection DOAJ
description Hepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microscopy the tumor resembled liver architecture, with polygonal atypical cells in nest formation and trabecular structures. Immunochemistry was positive for alfa-fetoprotein (AFP) and serum AFP was elevated. Hepatoid adenocarcinomas have been reported in multiple organs, being most commonly found in the stomach and the ovaries. Bladder compromise has been rarely described in the literature, and it has been associated with poor prognosis, low remission rates, and early metastasis.
format Article
id doaj-art-25bd8dea046743dc8248cbb4cc7239fb
institution OA Journals
issn 2090-6781
2090-679X
language English
publishDate 2016-01-01
publisher Wiley
record_format Article
series Case Reports in Pathology
spelling doaj-art-25bd8dea046743dc8248cbb4cc7239fb2025-08-20T02:04:30ZengWileyCase Reports in Pathology2090-67812090-679X2016-01-01201610.1155/2016/18718071871807Hepatoid Adenocarcinoma of the UrachusDaniel Fernando Gallego0Carlos Muñoz1Carlos Andrés Jimenez2Edwin Carrascal3Department of Pathology, University of Washington, Seattle, WA, USADepartment of Surgery, Mercy Medical Center, Baltimore, MD, USADepartment of Pathology, Fundacion Valle del Lili, Cali, ColombiaDepartment of Pathology, Universidad del Valle, Cali, ColombiaHepatoid adenocarcinoma of the urachus is a rare condition. We present the case of a 51-year-old female who developed abdominal pain and hematuria. Pelvic magnetic resonance imaging (MRI) reported an urachal mass with invasion to the bladder that was resected by partial cystectomy. On light microscopy the tumor resembled liver architecture, with polygonal atypical cells in nest formation and trabecular structures. Immunochemistry was positive for alfa-fetoprotein (AFP) and serum AFP was elevated. Hepatoid adenocarcinomas have been reported in multiple organs, being most commonly found in the stomach and the ovaries. Bladder compromise has been rarely described in the literature, and it has been associated with poor prognosis, low remission rates, and early metastasis.http://dx.doi.org/10.1155/2016/1871807
spellingShingle Daniel Fernando Gallego
Carlos Muñoz
Carlos Andrés Jimenez
Edwin Carrascal
Hepatoid Adenocarcinoma of the Urachus
Case Reports in Pathology
title Hepatoid Adenocarcinoma of the Urachus
title_full Hepatoid Adenocarcinoma of the Urachus
title_fullStr Hepatoid Adenocarcinoma of the Urachus
title_full_unstemmed Hepatoid Adenocarcinoma of the Urachus
title_short Hepatoid Adenocarcinoma of the Urachus
title_sort hepatoid adenocarcinoma of the urachus
url http://dx.doi.org/10.1155/2016/1871807
work_keys_str_mv AT danielfernandogallego hepatoidadenocarcinomaoftheurachus
AT carlosmunoz hepatoidadenocarcinomaoftheurachus
AT carlosandresjimenez hepatoidadenocarcinomaoftheurachus
AT edwincarrascal hepatoidadenocarcinomaoftheurachus