Three-Year Outcomes of Cross-Linking PLUS (Combined Cross-Linking with Femtosecond Laser Intracorneal Ring Segments Implantation) for Management of Keratoconus
Purpose. To analyze the results of three-year outcomes of combined epithelium-on cross-linking with femtosecond laser ICRS (cross-linking PLUS) for keratoconus management. Design. A retrospective multicenter clinical study. Methods. 43 eyes of 38 patients were subjected to preoperative and postopera...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2018/6907573 |
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| author | Mohammed Iqbal Hafez Saleem Hosam A. Ibrahim Elzembely Mortada Ahmed AboZaid Mohammed Elagouz Ahmed Mohamed Saeed Osama Ali Mohammed Ahmed Gad Kamel |
| author_facet | Mohammed Iqbal Hafez Saleem Hosam A. Ibrahim Elzembely Mortada Ahmed AboZaid Mohammed Elagouz Ahmed Mohamed Saeed Osama Ali Mohammed Ahmed Gad Kamel |
| author_sort | Mohammed Iqbal Hafez Saleem |
| collection | DOAJ |
| description | Purpose. To analyze the results of three-year outcomes of combined epithelium-on cross-linking with femtosecond laser ICRS (cross-linking PLUS) for keratoconus management. Design. A retrospective multicenter clinical study. Methods. 43 eyes of 38 patients were subjected to preoperative and postoperative UCVA, BCVA, refraction, Pentacam pachymetry, and keratometry examinations at 3-, 6-, 12-, 24-, and 36-month follow-up period. Results. The preoperative and postoperative mean UCVA was 1.30 ± 0.48 (logMAR ± SD) and 0.82 ± 0.22 respectively. The preoperative and postoperative mean BCVA was 0.90 ± 0.40 and 0.60 ± 0.30, respectively. The preoperative and postoperative mean K average was 50.63 ± 0.87 (D ± SD) and 45.56 ± 0.98, respectively. The preoperative and postoperative mean pachymetry was 471 ± 92.36 (μm ± SD) and 423 ± 39.58, respectively. The preoperative and postoperative mean astigmatism was 7.55 ± 1.75 and 3.39 ± 1.26, respectively. One eye showed ICRS edge exposure while 6 eyes showed progression of keratoconus. Conclusion. CXL PLUS was proved to be a successful procedure to halt progression (mainly by CXL) and to correct the refractive status of the keratoconic eye (mainly by ICRS). CXL PLUS performed a synergistic action correcting and maintaining the correction of both myopic and astigmatic components of keratoconus. |
| format | Article |
| id | doaj-art-25bb42048336428cac928dfc7f3b6b10 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-25bb42048336428cac928dfc7f3b6b102025-08-20T03:54:52ZengWileyJournal of Ophthalmology2090-004X2090-00582018-01-01201810.1155/2018/69075736907573Three-Year Outcomes of Cross-Linking PLUS (Combined Cross-Linking with Femtosecond Laser Intracorneal Ring Segments Implantation) for Management of KeratoconusMohammed Iqbal Hafez Saleem0Hosam A. Ibrahim Elzembely1Mortada Ahmed AboZaid2Mohammed Elagouz3Ahmed Mohamed Saeed4Osama Ali Mohammed5Ahmed Gad Kamel6Faculty of Medicine, Sohag University, Sohag, EgyptFaculty of Medicine, Minia University, Minia, EgyptFaculty of Medicine, Sohag University, Sohag, EgyptFaculty of Medicine, Sohag University, Sohag, EgyptFaculty of Medicine, Banha University, Banha, EgyptFaculty of Medicine, Sohag University, Sohag, EgyptFaculty of Medicine, Sohag University, Sohag, EgyptPurpose. To analyze the results of three-year outcomes of combined epithelium-on cross-linking with femtosecond laser ICRS (cross-linking PLUS) for keratoconus management. Design. A retrospective multicenter clinical study. Methods. 43 eyes of 38 patients were subjected to preoperative and postoperative UCVA, BCVA, refraction, Pentacam pachymetry, and keratometry examinations at 3-, 6-, 12-, 24-, and 36-month follow-up period. Results. The preoperative and postoperative mean UCVA was 1.30 ± 0.48 (logMAR ± SD) and 0.82 ± 0.22 respectively. The preoperative and postoperative mean BCVA was 0.90 ± 0.40 and 0.60 ± 0.30, respectively. The preoperative and postoperative mean K average was 50.63 ± 0.87 (D ± SD) and 45.56 ± 0.98, respectively. The preoperative and postoperative mean pachymetry was 471 ± 92.36 (μm ± SD) and 423 ± 39.58, respectively. The preoperative and postoperative mean astigmatism was 7.55 ± 1.75 and 3.39 ± 1.26, respectively. One eye showed ICRS edge exposure while 6 eyes showed progression of keratoconus. Conclusion. CXL PLUS was proved to be a successful procedure to halt progression (mainly by CXL) and to correct the refractive status of the keratoconic eye (mainly by ICRS). CXL PLUS performed a synergistic action correcting and maintaining the correction of both myopic and astigmatic components of keratoconus.http://dx.doi.org/10.1155/2018/6907573 |
| spellingShingle | Mohammed Iqbal Hafez Saleem Hosam A. Ibrahim Elzembely Mortada Ahmed AboZaid Mohammed Elagouz Ahmed Mohamed Saeed Osama Ali Mohammed Ahmed Gad Kamel Three-Year Outcomes of Cross-Linking PLUS (Combined Cross-Linking with Femtosecond Laser Intracorneal Ring Segments Implantation) for Management of Keratoconus Journal of Ophthalmology |
| title | Three-Year Outcomes of Cross-Linking PLUS (Combined Cross-Linking with Femtosecond Laser Intracorneal Ring Segments Implantation) for Management of Keratoconus |
| title_full | Three-Year Outcomes of Cross-Linking PLUS (Combined Cross-Linking with Femtosecond Laser Intracorneal Ring Segments Implantation) for Management of Keratoconus |
| title_fullStr | Three-Year Outcomes of Cross-Linking PLUS (Combined Cross-Linking with Femtosecond Laser Intracorneal Ring Segments Implantation) for Management of Keratoconus |
| title_full_unstemmed | Three-Year Outcomes of Cross-Linking PLUS (Combined Cross-Linking with Femtosecond Laser Intracorneal Ring Segments Implantation) for Management of Keratoconus |
| title_short | Three-Year Outcomes of Cross-Linking PLUS (Combined Cross-Linking with Femtosecond Laser Intracorneal Ring Segments Implantation) for Management of Keratoconus |
| title_sort | three year outcomes of cross linking plus combined cross linking with femtosecond laser intracorneal ring segments implantation for management of keratoconus |
| url | http://dx.doi.org/10.1155/2018/6907573 |
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