Diagnostic value of the wnt target and cancer-associated blood biomarker hPG80: ONCOPRO case-control prospective study

Diagnostic value of the wnt target and cancer-associated blood biomarker hPG80: ONCOPRO case-control prospective study

Abstract Background hPG80 (circulating progastrin), initially recognized for its oncogenic properties due to its direct link to the Wnt signaling pathway, is secreted by cancer cells and detectable in the blood of cancer patients. The ONCOPRO centralized case-control study (NCT03787056) was designed...

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Bibliographic Details
Main Authors: Benoit You, Sebastien Couraud, Philippe Ceruse, Lionel Badet, Philippe Paparel, Alice Durand, Marielle Guillet, Philippe Merle, Gaelle Lescuyer, Charles-André Philip, Francois Ducray, Mathieu Pioche, Lionel Karlin, Jean-Christophe Lifante, Olivier Glehen, Pierre-Adrien Bolze, Marion Chauvenet, Carole Langlois-Jacques, Fabien Subtil, Marie Piecyk, Aurore Carrot, Dominique Joubert, Alexandre Prieur, Berengere Vire, Sara Calattini, Lea Payen
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Biomarker Research
Subjects:
Biomarkers, tumor
Early detection of Cancer
Wnt signaling pathway
Prospective studies
Online Access:https://doi.org/10.1186/s40364-025-00793-z
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