Curdione protects vascular endothelial cells and atherosclerosis via the regulation of DNMT1-mediated ERBB4 promoter methylation

Curdione protects vascular endothelial cells and atherosclerosis via the regulation of DNMT1-mediated ERBB4 promoter methylation

Atherosclerosis (AS) is initiated by the activation of the endothelial cells, which is followed by a series of events that trigger the narrowing of blood vessels and the activation of inflammation. This study aimed to investigate in vitro the roles and underlying mechanisms of curdione in AS. Human...

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Bibliographic Details
Main Authors: Wu Yingbiao, Jin Can, Zhu Luoning, Zhang Xiaogang, Cong Xinpeng, Xing Budian, Ning Zhongping
Format: Article
Language:English
Published: De Gruyter 2025-07-01
Series:Open Medicine
Subjects:
atherosclerosis
curdione
dnmt1
erbb4
huvecs
ox-ldl
Online Access:https://doi.org/10.1515/med-2025-1223
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