Two unique cases of eosinophilic granulomatosis with polyangiitis in childhood treated with anti-interleukin-5 therapy: infantile-onset and submandibular salivary gland involvement

Two unique cases of eosinophilic granulomatosis with polyangiitis in childhood treated with anti-interleukin-5 therapy: infantile-onset and submandibular salivary gland involvement

Abstract Background ANCA-associated vasculitis is a systemic autoimmune disease involving small- and medium-sized blood vessels. Eosinophilic granulomatosis with polyangiitis (EGPA, previously Churg Strauss Syndrome) is the least common form in childhood with few cases reported. We present two uniqu...

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Bibliographic Details
Main Authors: Evangelia Constantine, Adam M. Bartholomeo, Inna Powers, Jerimiah L. Lysinger, Pia J. Hauk, Jordan Abbott, Heather H. de Keyser, Nicholas J. Gilman, Csaba Galambos, Angus Toland, Nicholas Willard, Jason Weinman, David Mong, Clara Lin, Jessica L. Bloom
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Eosinophilic granulomatosis with polyangiitis
EGPA
Churg Strauss
ANCA-associated vasculitis
Benralizumab
Mepolizumab
Online Access:https://doi.org/10.1186/s12969-025-01115-1
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