DNA nanotechnology-based strategies for gastric cancer diagnosis and therapy
Gastric cancer (GC) is a formidable adversary in the field of oncology. The low early diagnosis rate of GC results in a low overall survival rate. Therefore, early accurate diagnosis and effective treatment are the key to reduce the mortality of GC. With the advent of nanotechnology, researchers con...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Materials Today Bio |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006425000171 |
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| author | Congcong Li Tongyang Xu Guopeng Hou Yin Wang Qinrui Fu |
| author_facet | Congcong Li Tongyang Xu Guopeng Hou Yin Wang Qinrui Fu |
| author_sort | Congcong Li |
| collection | DOAJ |
| description | Gastric cancer (GC) is a formidable adversary in the field of oncology. The low early diagnosis rate of GC results in a low overall survival rate. Therefore, early accurate diagnosis and effective treatment are the key to reduce the mortality of GC. With the advent of nanotechnology, researchers continue to explore new possibilities for accurate diagnosis and effective treatment. One such breakthrough is the application of DNA nanotechnology. In this paper, the application of exciting DNA nanomaterials in the diagnosis and treatment of GC is discussed in depth. Firstly, the biomarkers related to GC and the diagnostic strategies related to DNA nanotechnology are summarized. Second, the latest research progress of DNA nanomaterials in the GC targeted therapy are summarized. Finally, the challenges and opportunities of DNA nanomaterials in the research and clinical application of GC are prospected. |
| format | Article |
| id | doaj-art-25a1370e5e0746118af49b35eabec975 |
| institution | Kabale University |
| issn | 2590-0064 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj-art-25a1370e5e0746118af49b35eabec9752025-01-17T04:52:17ZengElsevierMaterials Today Bio2590-00642025-02-0130101459DNA nanotechnology-based strategies for gastric cancer diagnosis and therapyCongcong Li0Tongyang Xu1Guopeng Hou2Yin Wang3Qinrui Fu4Corresponding author.; Key Laboratory of Maternal & Fetal Medicine of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Institute for Translational Medicine, College of Medicine, Qingdao University, Qingdao, 266073, ChinaKey Laboratory of Maternal & Fetal Medicine of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Institute for Translational Medicine, College of Medicine, Qingdao University, Qingdao, 266073, ChinaKey Laboratory of Maternal & Fetal Medicine of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Institute for Translational Medicine, College of Medicine, Qingdao University, Qingdao, 266073, ChinaCorresponding author.; Key Laboratory of Maternal & Fetal Medicine of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Institute for Translational Medicine, College of Medicine, Qingdao University, Qingdao, 266073, ChinaKey Laboratory of Maternal & Fetal Medicine of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Institute for Translational Medicine, College of Medicine, Qingdao University, Qingdao, 266073, ChinaGastric cancer (GC) is a formidable adversary in the field of oncology. The low early diagnosis rate of GC results in a low overall survival rate. Therefore, early accurate diagnosis and effective treatment are the key to reduce the mortality of GC. With the advent of nanotechnology, researchers continue to explore new possibilities for accurate diagnosis and effective treatment. One such breakthrough is the application of DNA nanotechnology. In this paper, the application of exciting DNA nanomaterials in the diagnosis and treatment of GC is discussed in depth. Firstly, the biomarkers related to GC and the diagnostic strategies related to DNA nanotechnology are summarized. Second, the latest research progress of DNA nanomaterials in the GC targeted therapy are summarized. Finally, the challenges and opportunities of DNA nanomaterials in the research and clinical application of GC are prospected.http://www.sciencedirect.com/science/article/pii/S2590006425000171DNA nanotechnologyGastric cancerDiagnosisTreatmentBiomarkerClinical application |
| spellingShingle | Congcong Li Tongyang Xu Guopeng Hou Yin Wang Qinrui Fu DNA nanotechnology-based strategies for gastric cancer diagnosis and therapy Materials Today Bio DNA nanotechnology Gastric cancer Diagnosis Treatment Biomarker Clinical application |
| title | DNA nanotechnology-based strategies for gastric cancer diagnosis and therapy |
| title_full | DNA nanotechnology-based strategies for gastric cancer diagnosis and therapy |
| title_fullStr | DNA nanotechnology-based strategies for gastric cancer diagnosis and therapy |
| title_full_unstemmed | DNA nanotechnology-based strategies for gastric cancer diagnosis and therapy |
| title_short | DNA nanotechnology-based strategies for gastric cancer diagnosis and therapy |
| title_sort | dna nanotechnology based strategies for gastric cancer diagnosis and therapy |
| topic | DNA nanotechnology Gastric cancer Diagnosis Treatment Biomarker Clinical application |
| url | http://www.sciencedirect.com/science/article/pii/S2590006425000171 |
| work_keys_str_mv | AT congcongli dnananotechnologybasedstrategiesforgastriccancerdiagnosisandtherapy AT tongyangxu dnananotechnologybasedstrategiesforgastriccancerdiagnosisandtherapy AT guopenghou dnananotechnologybasedstrategiesforgastriccancerdiagnosisandtherapy AT yinwang dnananotechnologybasedstrategiesforgastriccancerdiagnosisandtherapy AT qinruifu dnananotechnologybasedstrategiesforgastriccancerdiagnosisandtherapy |