Comparative Evaluation of the Efficacy of Mouthwash and Denture Cleanser in the Removal of Candida Albicans from Two Flexible Denture Base Materials – An In vitro Study

Background: Poly-methyl methacrylate is the most common denture base material but has limitations. Flexible denture base materials, such as Lucitone FRS and Valplast, were introduced to address these issues. Denture success depends on preventing microbial attachment and easy cleaning. This study eva...

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Main Authors: B. V. H. Ravi Teja, Jayakrishna Babu, Lokesh Sunkala, V. Bhanu Chander, K.V. Gurucharan Karthik, Jisa A. Alex
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-05-01
Series:Journal of Pharmacy and Bioallied Sciences
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Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_527_25
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Summary:Background: Poly-methyl methacrylate is the most common denture base material but has limitations. Flexible denture base materials, such as Lucitone FRS and Valplast, were introduced to address these issues. Denture success depends on preventing microbial attachment and easy cleaning. This study evaluates the efficacy of Clinsodent denture cleanser and 0.2% Chlorhexidine (Rexidine) mouthwash in removing Candida albicans from these materials. Methodology: Forty-eight specimens were subdivided into three groups, with eight in each. After inoculation with Candida albicans, samples were treated with distilled water (control), 0.2% Rexidine mouthwash, or Clinsodent cleanser. Colony counts were analyzed. Results: Rexidine mouthwash was more effective than Clinsodent. Valplast showed higher initial Candida growth, indicating Lucitone FRS is more resistant. Conclusion: 0.2% Rexidine mouthwash was superior in Candida removal, and Lucitone FRS exhibited greater resistance than Valplast.
ISSN:0976-4879
0975-7406