Ameliorative effects of coriander extract supplementation in mitigating nickel toxicity in grass carp (Ctenopharyngodon idella)
Abstract This research explored the ameliorative effects of coriander (Coriandrum sativum) seed extract supplementation in mitigating nickel (Ni) toxicity in fish. For this purpose, Ctenopharyngodon idella fingerlings (average weight: 12.35 ± 0.04 g/fish) were randomly assigned to 18 tanks, divided...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-13985-2 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849235210698227712 |
|---|---|
| author | Syed Muhammad Farhan Ali Shah Syed Makhdoom Hussain Weifang Wang Khalid A. Al-Ghanim Nadia Nazish |
| author_facet | Syed Muhammad Farhan Ali Shah Syed Makhdoom Hussain Weifang Wang Khalid A. Al-Ghanim Nadia Nazish |
| author_sort | Syed Muhammad Farhan Ali Shah |
| collection | DOAJ |
| description | Abstract This research explored the ameliorative effects of coriander (Coriandrum sativum) seed extract supplementation in mitigating nickel (Ni) toxicity in fish. For this purpose, Ctenopharyngodon idella fingerlings (average weight: 12.35 ± 0.04 g/fish) were randomly assigned to 18 tanks, divided into six groups with three replicates each. The six treatments were categorized as follows: the negative control group (NC) received no supplement and no Ni exposure, while the positive control group (PC) was exposed to 3.6 mg/L Ni without supplementation. The remaining four groups were fed dietary supplements with 1%, 2%, 3%, and 4% C. sativum, respectively, and were exposed to 3.6 mg/L Ni. Over the next 60 days, the trial continued. Waterborne Ni negatively impacted fish growth performance, blood profile, body composition, and antioxidant activity of C. idella. On the other hand, dietary C. sativum improved fish health and successfully reduced Ni toxic potential. Notably, 1% C. sativum supplementation enhanced growth performance (weight gain: 22.82 g; weight gain percentage: 185.74%) and improved carcass quality (protein: 14.65%; fat: 4.15%; ash: 2.74%; moisture: 74.84%). Additionally, it improved blood indices (RBCs: 2.45 × 106 mm−3; WBCs: 14.21 × 103 mm−3) and antioxidant activity (SOD: 30.26 U/mg; CAT: 3.66 U/mg; GST: 48.35 U/mg), significantly improving serum biochemical indices and mitigating Ni toxicity. In summary, the results suggest that dietary supplementation with 1% C. sativum effectively reduces Ni toxicity in C. idella. |
| format | Article |
| id | doaj-art-25795f0b7d194b8d8d0a0847f85342e4 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-25795f0b7d194b8d8d0a0847f85342e42025-08-20T04:02:51ZengNature PortfolioScientific Reports2045-23222025-08-0115111110.1038/s41598-025-13985-2Ameliorative effects of coriander extract supplementation in mitigating nickel toxicity in grass carp (Ctenopharyngodon idella)Syed Muhammad Farhan Ali Shah0Syed Makhdoom Hussain1Weifang Wang2Khalid A. Al-Ghanim3Nadia Nazish4Fish Nutrition Laboratory, Department of Zoology, Government College University FaisalabadFish Nutrition Laboratory, Department of Zoology, Government College University FaisalabadState Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery SciencesDepartment of Zoology, College of Science, King Saud UniversityDepartment of Zoology, University of SialkotAbstract This research explored the ameliorative effects of coriander (Coriandrum sativum) seed extract supplementation in mitigating nickel (Ni) toxicity in fish. For this purpose, Ctenopharyngodon idella fingerlings (average weight: 12.35 ± 0.04 g/fish) were randomly assigned to 18 tanks, divided into six groups with three replicates each. The six treatments were categorized as follows: the negative control group (NC) received no supplement and no Ni exposure, while the positive control group (PC) was exposed to 3.6 mg/L Ni without supplementation. The remaining four groups were fed dietary supplements with 1%, 2%, 3%, and 4% C. sativum, respectively, and were exposed to 3.6 mg/L Ni. Over the next 60 days, the trial continued. Waterborne Ni negatively impacted fish growth performance, blood profile, body composition, and antioxidant activity of C. idella. On the other hand, dietary C. sativum improved fish health and successfully reduced Ni toxic potential. Notably, 1% C. sativum supplementation enhanced growth performance (weight gain: 22.82 g; weight gain percentage: 185.74%) and improved carcass quality (protein: 14.65%; fat: 4.15%; ash: 2.74%; moisture: 74.84%). Additionally, it improved blood indices (RBCs: 2.45 × 106 mm−3; WBCs: 14.21 × 103 mm−3) and antioxidant activity (SOD: 30.26 U/mg; CAT: 3.66 U/mg; GST: 48.35 U/mg), significantly improving serum biochemical indices and mitigating Ni toxicity. In summary, the results suggest that dietary supplementation with 1% C. sativum effectively reduces Ni toxicity in C. idella.https://doi.org/10.1038/s41598-025-13985-2Antioxidant activityBiochemical analysisCoriandrum sativumCtenopharyngodon IdellaGrowthNickel toxicity |
| spellingShingle | Syed Muhammad Farhan Ali Shah Syed Makhdoom Hussain Weifang Wang Khalid A. Al-Ghanim Nadia Nazish Ameliorative effects of coriander extract supplementation in mitigating nickel toxicity in grass carp (Ctenopharyngodon idella) Scientific Reports Antioxidant activity Biochemical analysis Coriandrum sativum Ctenopharyngodon Idella Growth Nickel toxicity |
| title | Ameliorative effects of coriander extract supplementation in mitigating nickel toxicity in grass carp (Ctenopharyngodon idella) |
| title_full | Ameliorative effects of coriander extract supplementation in mitigating nickel toxicity in grass carp (Ctenopharyngodon idella) |
| title_fullStr | Ameliorative effects of coriander extract supplementation in mitigating nickel toxicity in grass carp (Ctenopharyngodon idella) |
| title_full_unstemmed | Ameliorative effects of coriander extract supplementation in mitigating nickel toxicity in grass carp (Ctenopharyngodon idella) |
| title_short | Ameliorative effects of coriander extract supplementation in mitigating nickel toxicity in grass carp (Ctenopharyngodon idella) |
| title_sort | ameliorative effects of coriander extract supplementation in mitigating nickel toxicity in grass carp ctenopharyngodon idella |
| topic | Antioxidant activity Biochemical analysis Coriandrum sativum Ctenopharyngodon Idella Growth Nickel toxicity |
| url | https://doi.org/10.1038/s41598-025-13985-2 |
| work_keys_str_mv | AT syedmuhammadfarhanalishah ameliorativeeffectsofcorianderextractsupplementationinmitigatingnickeltoxicityingrasscarpctenopharyngodonidella AT syedmakhdoomhussain ameliorativeeffectsofcorianderextractsupplementationinmitigatingnickeltoxicityingrasscarpctenopharyngodonidella AT weifangwang ameliorativeeffectsofcorianderextractsupplementationinmitigatingnickeltoxicityingrasscarpctenopharyngodonidella AT khalidaalghanim ameliorativeeffectsofcorianderextractsupplementationinmitigatingnickeltoxicityingrasscarpctenopharyngodonidella AT nadianazish ameliorativeeffectsofcorianderextractsupplementationinmitigatingnickeltoxicityingrasscarpctenopharyngodonidella |