The Application of Bactericidal Silver Nanoparticles in Wound Treatment

Even with the prevalence of wounds, the medical technol‐ ogy for efficiently managing skin damage is still primitive. The disruption of any of the numerous healing processes can lead to problems in the time-sensitive healing actions of the dermal and epidermal layers. Bacterial infection is one of t...

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Main Authors: Geewoo Nam, Sabarinathan Rangasamy, Baskaran Purushothaman, Joon Myong Song
Format: Article
Language:English
Published: Wiley 2015-07-01
Series:Nanomaterials and Nanotechnology
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Online Access:http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/the-application-of-bactericidal-silver-nanoparticles-in-wound-treatment
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author Geewoo Nam
Sabarinathan Rangasamy
Baskaran Purushothaman
Joon Myong Song
author_facet Geewoo Nam
Sabarinathan Rangasamy
Baskaran Purushothaman
Joon Myong Song
author_sort Geewoo Nam
collection DOAJ
description Even with the prevalence of wounds, the medical technol‐ ogy for efficiently managing skin damage is still primitive. The disruption of any of the numerous healing processes can lead to problems in the time-sensitive healing actions of the dermal and epidermal layers. Bacterial infection is one of the major obstacles to proper wound healing as it poses a danger of causing long-term negative effects. Keeping the wound free of bacteria is imperative to the proper and hasty repair of dermal wounds. Silver has been widely used to treat wounds for its bactericidal properties. Although the mechanism of silver’s antibacterial action is not fully understood, it exhibits a significant antimicrobial efficacy against a wide spectrum of bacterial species. A number of different approaches to the mechanism are reported and presented in this review. Silver nanoparticles (AgNPs) have been reported to exhibit enhanced antibac‐ terial activity due to their increased surface-area-to-volume ratio. AgNPs are capable of various modifications, signifi‐ cantly broadening the therapeutic properties of the mate‐ rial as a result. This review explores the different aspects of silver and silver nanoparticles, and their antibacterial properties, which can be applied in the field of wound treatments.
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series Nanomaterials and Nanotechnology
spelling doaj-art-2576f3d7b88d4c9fa8a70b78d76cc1f82025-08-20T03:54:52ZengWileyNanomaterials and Nanotechnology1847-98042015-07-01523http://dx.doi.org/10.5772/6091848789The Application of Bactericidal Silver Nanoparticles in Wound TreatmentGeewoo NamSabarinathan RangasamyBaskaran PurushothamanJoon Myong SongEven with the prevalence of wounds, the medical technol‐ ogy for efficiently managing skin damage is still primitive. The disruption of any of the numerous healing processes can lead to problems in the time-sensitive healing actions of the dermal and epidermal layers. Bacterial infection is one of the major obstacles to proper wound healing as it poses a danger of causing long-term negative effects. Keeping the wound free of bacteria is imperative to the proper and hasty repair of dermal wounds. Silver has been widely used to treat wounds for its bactericidal properties. Although the mechanism of silver’s antibacterial action is not fully understood, it exhibits a significant antimicrobial efficacy against a wide spectrum of bacterial species. A number of different approaches to the mechanism are reported and presented in this review. Silver nanoparticles (AgNPs) have been reported to exhibit enhanced antibac‐ terial activity due to their increased surface-area-to-volume ratio. AgNPs are capable of various modifications, signifi‐ cantly broadening the therapeutic properties of the mate‐ rial as a result. This review explores the different aspects of silver and silver nanoparticles, and their antibacterial properties, which can be applied in the field of wound treatments.http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/the-application-of-bactericidal-silver-nanoparticles-in-wound-treatmentwound treatmentantibacterialsilversilver nanoparticles
spellingShingle Geewoo Nam
Sabarinathan Rangasamy
Baskaran Purushothaman
Joon Myong Song
The Application of Bactericidal Silver Nanoparticles in Wound Treatment
Nanomaterials and Nanotechnology
wound treatment
antibacterial
silver
silver nanoparticles
title The Application of Bactericidal Silver Nanoparticles in Wound Treatment
title_full The Application of Bactericidal Silver Nanoparticles in Wound Treatment
title_fullStr The Application of Bactericidal Silver Nanoparticles in Wound Treatment
title_full_unstemmed The Application of Bactericidal Silver Nanoparticles in Wound Treatment
title_short The Application of Bactericidal Silver Nanoparticles in Wound Treatment
title_sort application of bactericidal silver nanoparticles in wound treatment
topic wound treatment
antibacterial
silver
silver nanoparticles
url http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/the-application-of-bactericidal-silver-nanoparticles-in-wound-treatment
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