Development and Clinical Application of High-Magnification Electronic Endoscope

This article introduces a high-magnification electronic endoscope system that utilizes a continuous zoom optical design, enabling high-magnification imaging at the cellular level. By selecting an appropriate initial retrofocus structure, the optimized modulation transfer function (MTF) curve of the...

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Main Authors: Fan WANG, Jiansong XIA, Hui YANG, Guofei YAN, Jiaying HE, Liqiang WANG
Format: Article
Language:zho
Published: Editorial Office of Chinese Journal of Medical Instrumentation 2024-11-01
Series:Zhongguo yiliao qixie zazhi
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Online Access:https://zgylqxzz.xml-journal.net/article/doi/10.12455/j.issn.1671-7104.240069
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author Fan WANG
Jiansong XIA
Hui YANG
Guofei YAN
Jiaying HE
Liqiang WANG
author_facet Fan WANG
Jiansong XIA
Hui YANG
Guofei YAN
Jiaying HE
Liqiang WANG
author_sort Fan WANG
collection DOAJ
description This article introduces a high-magnification electronic endoscope system that utilizes a continuous zoom optical design, enabling high-magnification imaging at the cellular level. By selecting an appropriate initial retrofocus structure, the optimized modulation transfer function (MTF) curve of the zoom objective lens approaches the diffraction limit. Additionally, the tip and operation parts of the system incorporate modular gas-tight sealing and multiple layers of protective structure. The design employs efficient sealing materials and precise packaging techniques to ensure the system’s sealing performance. The experimental results indicate that, under conventional imaging, the resolution is equivalent to 39.37 μm in object space, and the field of view angle is larger than 140 degrees. At magnified imaging, the resolution is equivalent to 2.78 μm in object space, and the observed actual field of view is greater than 800 μm×700 μm. When used with a 26-inch display monitor, the high-magnification electronic endoscope can achieve 500× optical magnification, allowing for the observation of features at the cellular level. Currently, this product has successfully achieved mass production and has undergone multiple animal trials, demonstrating its wide range of potential applications and significant clinical value.
format Article
id doaj-art-2574792dbe0348728f4f01c6765adeb7
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issn 1671-7104
language zho
publishDate 2024-11-01
publisher Editorial Office of Chinese Journal of Medical Instrumentation
record_format Article
series Zhongguo yiliao qixie zazhi
spelling doaj-art-2574792dbe0348728f4f01c6765adeb72025-08-20T02:19:33ZzhoEditorial Office of Chinese Journal of Medical InstrumentationZhongguo yiliao qixie zazhi1671-71042024-11-0148665866310.12455/j.issn.1671-7104.2400692024-0069Development and Clinical Application of High-Magnification Electronic EndoscopeFan WANG0Jiansong XIA1Hui YANG2Guofei YAN3Jiaying HE4Liqiang WANG5Zhejiang Center for Medical Device Evaluation, Hangzhou, 311121Zhejiang Center for Medical Device Evaluation, Hangzhou, 311121Zhejiang Center for Medical Device Evaluation, Hangzhou, 311121Zhejiang Center for Medical Device Evaluation, Hangzhou, 311121College of Optical Science and Engineering, Zhejiang University, Hangzhou, 310027College of Optical Science and Engineering, Zhejiang University, Hangzhou, 310027This article introduces a high-magnification electronic endoscope system that utilizes a continuous zoom optical design, enabling high-magnification imaging at the cellular level. By selecting an appropriate initial retrofocus structure, the optimized modulation transfer function (MTF) curve of the zoom objective lens approaches the diffraction limit. Additionally, the tip and operation parts of the system incorporate modular gas-tight sealing and multiple layers of protective structure. The design employs efficient sealing materials and precise packaging techniques to ensure the system’s sealing performance. The experimental results indicate that, under conventional imaging, the resolution is equivalent to 39.37 μm in object space, and the field of view angle is larger than 140 degrees. At magnified imaging, the resolution is equivalent to 2.78 μm in object space, and the observed actual field of view is greater than 800 μm×700 μm. When used with a 26-inch display monitor, the high-magnification electronic endoscope can achieve 500× optical magnification, allowing for the observation of features at the cellular level. Currently, this product has successfully achieved mass production and has undergone multiple animal trials, demonstrating its wide range of potential applications and significant clinical value.https://zgylqxzz.xml-journal.net/article/doi/10.12455/j.issn.1671-7104.240069high-magnification electronic endoscopeclinical applicationszoom optical systemsealing process development
spellingShingle Fan WANG
Jiansong XIA
Hui YANG
Guofei YAN
Jiaying HE
Liqiang WANG
Development and Clinical Application of High-Magnification Electronic Endoscope
Zhongguo yiliao qixie zazhi
high-magnification electronic endoscope
clinical applications
zoom optical system
sealing process development
title Development and Clinical Application of High-Magnification Electronic Endoscope
title_full Development and Clinical Application of High-Magnification Electronic Endoscope
title_fullStr Development and Clinical Application of High-Magnification Electronic Endoscope
title_full_unstemmed Development and Clinical Application of High-Magnification Electronic Endoscope
title_short Development and Clinical Application of High-Magnification Electronic Endoscope
title_sort development and clinical application of high magnification electronic endoscope
topic high-magnification electronic endoscope
clinical applications
zoom optical system
sealing process development
url https://zgylqxzz.xml-journal.net/article/doi/10.12455/j.issn.1671-7104.240069
work_keys_str_mv AT fanwang developmentandclinicalapplicationofhighmagnificationelectronicendoscope
AT jiansongxia developmentandclinicalapplicationofhighmagnificationelectronicendoscope
AT huiyang developmentandclinicalapplicationofhighmagnificationelectronicendoscope
AT guofeiyan developmentandclinicalapplicationofhighmagnificationelectronicendoscope
AT jiayinghe developmentandclinicalapplicationofhighmagnificationelectronicendoscope
AT liqiangwang developmentandclinicalapplicationofhighmagnificationelectronicendoscope