Measures of diabetic retinopathy treatment coverage: protocol for a methodological review

Introduction Diabetic retinopathy is one of the leading causes of vision impairment globally. Alongside the systemic control of diabetes and timely detection of diabetic retinopathy, the prompt initiation and completion of treatment is essential to prevent vision loss. Routine monitoring of access t...

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Main Authors: Stuart Keel, Matthew J Burton, Jacqueline Ramke, Iris Gordon, Jennifer Evans, Nyawira Mwangi, Covadonga Bascaran, Rinki Murphy, Pushkar Raj Silwal, Subash Bhatta, Nayana Pant, Nimisha Chabba
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Language:English
Published: BMJ Publishing Group 2025-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/3/e092081.full
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author Stuart Keel
Matthew J Burton
Jacqueline Ramke
Iris Gordon
Jennifer Evans
Nyawira Mwangi
Covadonga Bascaran
Rinki Murphy
Pushkar Raj Silwal
Subash Bhatta
Nayana Pant
Nimisha Chabba
author_facet Stuart Keel
Matthew J Burton
Jacqueline Ramke
Iris Gordon
Jennifer Evans
Nyawira Mwangi
Covadonga Bascaran
Rinki Murphy
Pushkar Raj Silwal
Subash Bhatta
Nayana Pant
Nimisha Chabba
author_sort Stuart Keel
collection DOAJ
description Introduction Diabetic retinopathy is one of the leading causes of vision impairment globally. Alongside the systemic control of diabetes and timely detection of diabetic retinopathy, the prompt initiation and completion of treatment is essential to prevent vision loss. Routine monitoring of access to retinal screening services for the detection of diabetic retinopathy is common, while monitoring of coverage of subsequent treatment services is far less common. When diabetic retinopathy treatment coverage is assessed, there is great variability in how it is defined and reported. If a definition of treatment coverage could be standardised, the monitoring of the quality of diabetes eye care could more readily be compared between settings and over time. The aim of this review is to summarise how diabetic retinopathy treatment coverage has been measured in published studies and the extent to which these have been disaggregated by population groups.Methods and analysis A search will be conducted on Medline and Embase without any language restrictions, for cohort and cross-sectional studies published from 1 January 2015 that report diabetic retinopathy treatment coverage for adults with diabetic retinopathy and/or macular oedema. We will include studies from any world region reporting diabetic retinopathy treatment coverage for one or more of: (1) laser photocoagulation; (2) intravitreal injections of antivascular endothelial growth factor agents; (3) intravitreal injections of corticosteroids; (4) vitrectomy. The PROGRESS framework (place of residence, race/ethnicity/culture/language, occupation, gender/sex, religion, education, socioeconomic status and social capital) will be used to assess disaggregation by population groups. Two investigators will independently screen studies and extract relevant data. Data will be synthesised descriptively to outline the full range of definitions of diabetic retinopathy treatment coverage in the literature and identify the common sources of data used.Ethics and dissemination This review will only include published data; thus, no ethical approval will be sought. The findings of this review will be published in a peer-reviewed journal and presented at relevant conferences. The findings will also be considered in conjunction with an ongoing review on retinal screening for diabetic retinopathy to develop indicators for monitoring of services along the diabetes eye care pathway, which may include an indicator of effective service coverage.Registration Open Science Framework registration 6/08/2024: https://osf.io/5b93m
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spelling doaj-art-25706d0f31f444a3a68f2db059277e0c2025-08-20T02:50:27ZengBMJ Publishing GroupBMJ Open2044-60552025-03-0115310.1136/bmjopen-2024-092081Measures of diabetic retinopathy treatment coverage: protocol for a methodological reviewStuart Keel0Matthew J Burton1Jacqueline Ramke2Iris Gordon3Jennifer Evans4Nyawira Mwangi5Covadonga Bascaran6Rinki Murphy7Pushkar Raj Silwal8Subash Bhatta9Nayana Pant10Nimisha Chabba11Department of Noncommunicable Diseases, World Health Organization, Geneva, SwitzerlandInternational Centre for Eye Health, London School of Hygiene & Tropical Medicine, London, England, UKSchool of Optometry and Vision Science, University of Auckland, Auckland, New ZealandInternational Centre for Eye Health, London School of Hygiene & Tropical Medicine, London, England, UKInternational Centre for Eye Health, London School of Hygiene & Tropical Medicine, London, England, UKKenya Medical Training College, Nairobi, KenyaInternational Centre for Eye Health, London School of Hygiene & Tropical Medicine, London, England, UKSchool of Medicine, The University of Auckland, Auckland, New ZealandSchool of Optometry and Vision Science, University of Auckland, Auckland, New ZealandPacific Eye Institute, Suva, FijiDrishti Eye Care Hospital, Kathmandu, NepalSchool of Optometry and Vision Science, University of Auckland, Auckland, New ZealandIntroduction Diabetic retinopathy is one of the leading causes of vision impairment globally. Alongside the systemic control of diabetes and timely detection of diabetic retinopathy, the prompt initiation and completion of treatment is essential to prevent vision loss. Routine monitoring of access to retinal screening services for the detection of diabetic retinopathy is common, while monitoring of coverage of subsequent treatment services is far less common. When diabetic retinopathy treatment coverage is assessed, there is great variability in how it is defined and reported. If a definition of treatment coverage could be standardised, the monitoring of the quality of diabetes eye care could more readily be compared between settings and over time. The aim of this review is to summarise how diabetic retinopathy treatment coverage has been measured in published studies and the extent to which these have been disaggregated by population groups.Methods and analysis A search will be conducted on Medline and Embase without any language restrictions, for cohort and cross-sectional studies published from 1 January 2015 that report diabetic retinopathy treatment coverage for adults with diabetic retinopathy and/or macular oedema. We will include studies from any world region reporting diabetic retinopathy treatment coverage for one or more of: (1) laser photocoagulation; (2) intravitreal injections of antivascular endothelial growth factor agents; (3) intravitreal injections of corticosteroids; (4) vitrectomy. The PROGRESS framework (place of residence, race/ethnicity/culture/language, occupation, gender/sex, religion, education, socioeconomic status and social capital) will be used to assess disaggregation by population groups. Two investigators will independently screen studies and extract relevant data. Data will be synthesised descriptively to outline the full range of definitions of diabetic retinopathy treatment coverage in the literature and identify the common sources of data used.Ethics and dissemination This review will only include published data; thus, no ethical approval will be sought. The findings of this review will be published in a peer-reviewed journal and presented at relevant conferences. The findings will also be considered in conjunction with an ongoing review on retinal screening for diabetic retinopathy to develop indicators for monitoring of services along the diabetes eye care pathway, which may include an indicator of effective service coverage.Registration Open Science Framework registration 6/08/2024: https://osf.io/5b93mhttps://bmjopen.bmj.com/content/15/3/e092081.full
spellingShingle Stuart Keel
Matthew J Burton
Jacqueline Ramke
Iris Gordon
Jennifer Evans
Nyawira Mwangi
Covadonga Bascaran
Rinki Murphy
Pushkar Raj Silwal
Subash Bhatta
Nayana Pant
Nimisha Chabba
Measures of diabetic retinopathy treatment coverage: protocol for a methodological review
BMJ Open
title Measures of diabetic retinopathy treatment coverage: protocol for a methodological review
title_full Measures of diabetic retinopathy treatment coverage: protocol for a methodological review
title_fullStr Measures of diabetic retinopathy treatment coverage: protocol for a methodological review
title_full_unstemmed Measures of diabetic retinopathy treatment coverage: protocol for a methodological review
title_short Measures of diabetic retinopathy treatment coverage: protocol for a methodological review
title_sort measures of diabetic retinopathy treatment coverage protocol for a methodological review
url https://bmjopen.bmj.com/content/15/3/e092081.full
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