Postradiation Cranial Brachial Plexus Neuropathy: Clinical Examination and Electrophysiologic Diagnosis
A muscular man in his early twenties was treated with radiation (7000 cGy in 33 fractions) for nasopharyngeal carcinoma. Seven years later, he presented with gradually progressive painless proximal right arm weakness and paresthesia, mild dysarthria, and a sensation of pharyngeal tightness. A neurol...
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| Language: | English |
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American College of Physicians
2024-12-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2024.0293 |
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| author | Lemuel E. Gordon-Hackshaw Nathan A. Seven Nathan P. Young |
| author_facet | Lemuel E. Gordon-Hackshaw Nathan A. Seven Nathan P. Young |
| author_sort | Lemuel E. Gordon-Hackshaw |
| collection | DOAJ |
| description | A muscular man in his early twenties was treated with radiation (7000 cGy in 33 fractions) for nasopharyngeal carcinoma. Seven years later, he presented with gradually progressive painless proximal right arm weakness and paresthesia, mild dysarthria, and a sensation of pharyngeal tightness. A neurologic examination demonstrated weakness and atrophy of the tongue and right upper limb with abnormal movements of the tongue. Electromyography demonstrated neurogenic limb abnormalities and tongue myokymia, confirming a diagnosis of radiation neurotoxicity. |
| format | Article |
| id | doaj-art-2562822e7daf4cc9973b3f8dccfa759a |
| institution | DOAJ |
| issn | 2767-7664 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-2562822e7daf4cc9973b3f8dccfa759a2025-08-20T03:18:48ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-12-0131210.7326/aimcc.2024.0293Postradiation Cranial Brachial Plexus Neuropathy: Clinical Examination and Electrophysiologic DiagnosisLemuel E. Gordon-Hackshaw0Nathan A. Seven1Nathan P. Young21Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota2Department of Neurology, Mayo Clinic, Rochester, Minnesota2Department of Neurology, Mayo Clinic, Rochester, MinnesotaA muscular man in his early twenties was treated with radiation (7000 cGy in 33 fractions) for nasopharyngeal carcinoma. Seven years later, he presented with gradually progressive painless proximal right arm weakness and paresthesia, mild dysarthria, and a sensation of pharyngeal tightness. A neurologic examination demonstrated weakness and atrophy of the tongue and right upper limb with abnormal movements of the tongue. Electromyography demonstrated neurogenic limb abnormalities and tongue myokymia, confirming a diagnosis of radiation neurotoxicity.https://www.acpjournals.org/doi/10.7326/aimcc.2024.0293 |
| spellingShingle | Lemuel E. Gordon-Hackshaw Nathan A. Seven Nathan P. Young Postradiation Cranial Brachial Plexus Neuropathy: Clinical Examination and Electrophysiologic Diagnosis Annals of Internal Medicine: Clinical Cases |
| title | Postradiation Cranial Brachial Plexus Neuropathy: Clinical Examination and Electrophysiologic Diagnosis |
| title_full | Postradiation Cranial Brachial Plexus Neuropathy: Clinical Examination and Electrophysiologic Diagnosis |
| title_fullStr | Postradiation Cranial Brachial Plexus Neuropathy: Clinical Examination and Electrophysiologic Diagnosis |
| title_full_unstemmed | Postradiation Cranial Brachial Plexus Neuropathy: Clinical Examination and Electrophysiologic Diagnosis |
| title_short | Postradiation Cranial Brachial Plexus Neuropathy: Clinical Examination and Electrophysiologic Diagnosis |
| title_sort | postradiation cranial brachial plexus neuropathy clinical examination and electrophysiologic diagnosis |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2024.0293 |
| work_keys_str_mv | AT lemuelegordonhackshaw postradiationcranialbrachialplexusneuropathyclinicalexaminationandelectrophysiologicdiagnosis AT nathanaseven postradiationcranialbrachialplexusneuropathyclinicalexaminationandelectrophysiologicdiagnosis AT nathanpyoung postradiationcranialbrachialplexusneuropathyclinicalexaminationandelectrophysiologicdiagnosis |