Hematological parameters for a single oral intake of sodium iodide (Na131I) to the body of experimental rats

Study of hematological parameters (number of erythrocytes, leukocytes and leukogram) of peripheral blood of laboratory Wistar rats after administration of single oral radionuclide 131I in a solution of sodium iodide (Na131I) with activities of 3.3, 19.16, 113.8 and 327.0 kBq per animal was performed...

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Main Authors: T. V. Tsyganok, N. K. Rodionova, I. P. Drozd, L. V. Tarasenko, V. I. Fedorchenko
Format: Article
Language:English
Published: Institute for Nuclear Research, National Academy of Sciences of Ukraine 2015-12-01
Series:Ядерна фізика та енергетика
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Online Access:http://jnpae.kinr.kiev.ua/16.4/html/16.4.0374.html
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author T. V. Tsyganok
N. K. Rodionova
I. P. Drozd
L. V. Tarasenko
V. I. Fedorchenko
author_facet T. V. Tsyganok
N. K. Rodionova
I. P. Drozd
L. V. Tarasenko
V. I. Fedorchenko
author_sort T. V. Tsyganok
collection DOAJ
description Study of hematological parameters (number of erythrocytes, leukocytes and leukogram) of peripheral blood of laboratory Wistar rats after administration of single oral radionuclide 131I in a solution of sodium iodide (Na131I) with activities of 3.3, 19.16, 113.8 and 327.0 kBq per animal was performed. Number of red blood cells in the bloodstream throughout the observation period was not significantly changed. Number of white blood cell count increased. The increase of activity injected by radioiodine caused reliably greater degree of significant increase in the number of leukocytes throughout the experiment due to increase of the absolute number of lymphocytes.
format Article
id doaj-art-255604d257ec4f93b5437a2a87630ab6
institution Kabale University
issn 1818-331X
2074-0565
language English
publishDate 2015-12-01
publisher Institute for Nuclear Research, National Academy of Sciences of Ukraine
record_format Article
series Ядерна фізика та енергетика
spelling doaj-art-255604d257ec4f93b5437a2a87630ab62025-08-20T03:54:52ZengInstitute for Nuclear Research, National Academy of Sciences of UkraineЯдерна фізика та енергетика1818-331X2074-05652015-12-01164374380Hematological parameters for a single oral intake of sodium iodide (Na131I) to the body of experimental ratsT. V. Tsyganok0N. K. Rodionova1I. P. Drozd2L. V. Tarasenko3V. I. Fedorchenko4Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine R. Kavetsky Institute for Experimental Pathology, Oncology & Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine Study of hematological parameters (number of erythrocytes, leukocytes and leukogram) of peripheral blood of laboratory Wistar rats after administration of single oral radionuclide 131I in a solution of sodium iodide (Na131I) with activities of 3.3, 19.16, 113.8 and 327.0 kBq per animal was performed. Number of red blood cells in the bloodstream throughout the observation period was not significantly changed. Number of white blood cell count increased. The increase of activity injected by radioiodine caused reliably greater degree of significant increase in the number of leukocytes throughout the experiment due to increase of the absolute number of lymphocytes.http://jnpae.kinr.kiev.ua/16.4/html/16.4.0374.htmllaboratory rats131Іperipheral bloodleukocytesleukogram
spellingShingle T. V. Tsyganok
N. K. Rodionova
I. P. Drozd
L. V. Tarasenko
V. I. Fedorchenko
Hematological parameters for a single oral intake of sodium iodide (Na131I) to the body of experimental rats
Ядерна фізика та енергетика
laboratory rats
131І
peripheral blood
leukocytes
leukogram
title Hematological parameters for a single oral intake of sodium iodide (Na131I) to the body of experimental rats
title_full Hematological parameters for a single oral intake of sodium iodide (Na131I) to the body of experimental rats
title_fullStr Hematological parameters for a single oral intake of sodium iodide (Na131I) to the body of experimental rats
title_full_unstemmed Hematological parameters for a single oral intake of sodium iodide (Na131I) to the body of experimental rats
title_short Hematological parameters for a single oral intake of sodium iodide (Na131I) to the body of experimental rats
title_sort hematological parameters for a single oral intake of sodium iodide na131i to the body of experimental rats
topic laboratory rats
131І
peripheral blood
leukocytes
leukogram
url http://jnpae.kinr.kiev.ua/16.4/html/16.4.0374.html
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AT ipdrozd hematologicalparametersforasingleoralintakeofsodiumiodidena131itothebodyofexperimentalrats
AT lvtarasenko hematologicalparametersforasingleoralintakeofsodiumiodidena131itothebodyofexperimentalrats
AT vifedorchenko hematologicalparametersforasingleoralintakeofsodiumiodidena131itothebodyofexperimentalrats