Isolation and identification of a new porcine astrovirus 5 demonstrated that oxidative stress enhances porcine astrovirus replication

Isolation and identification of a new porcine astrovirus 5 demonstrated that oxidative stress enhances porcine astrovirus replication

Abstract Background Porcine astrovirus (PAstV) poses a major risk to the pig industry by causing diarrhea in suckling piglets. Despite its global prevalence and five genotypes, the virus’s pathogenic mechanism is not well understood due to difficulties in isolating and culturing it in vitro. Studyin...

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Main Authors: Yiyang Du, Yibin Qin, Xiaoying Feng, Yuhang Luo, Yueqing Lv, Shichuan Song, Xiaofang Wei, Kang Ouyang, Yeshi Yin, Ying Chen, Zuzhang Wei, Weijian Huang, Yifeng Qin
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Veterinary Research
Subjects:
Porcine astrovirus 5
Isolation
Genomic analysis
Oxidative stress
Mitochondrial damage
Online Access:https://doi.org/10.1186/s12917-025-04939-x
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