Role of arbutin in the inhibition of FBXO5 in hepatocellular carcinoma

Role of arbutin in the inhibition of FBXO5 in hepatocellular carcinoma

Abstract Purpose This work investigated the effect of FBXO5 in hepatocellular carcinoma (HCC) and the mechanism of action of arbutin in its inhibition. Methods FBXO5 mRNA and protein expressions in the tumor were assessed using TCGA, ICGC and HPA databases. Cox regression analysis and Kaplan–Meier s...

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Bibliographic Details
Main Authors: Shuo Zhang, Kai Yao, Yangjing Pi, Sen Yang, Zheng Huang, Xueshan Pan, Tonggang Li
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Discover Oncology
Subjects:
Arbutin
HCC
FBXO5
Cell cycle
Online Access:https://doi.org/10.1007/s12672-024-01729-z
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