New approaches to reduce ulcerogenity of nonsteroidal anti-inflammatory drugs: achievements, unsolved issues and ways to optimize

Analysis of the domestic and foreign literature sources devoted to the study of pathogenetic mechanisms of gastropathy caused by non-steroidal anti-inflammatory drugs was done. Current approaches of prevention and treatment of NSAID-induced gastropathy were lined. The appropriateness of drugs with p...

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Main Authors: F. V. Hladkykh, N. H. Stepaniuk
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2014-04-01
Series:Zaporožskij Medicinskij Žurnal
Subjects:
Online Access:http://zmj.zsmu.edu.ua/article/view/25437/22932
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author F. V. Hladkykh
N. H. Stepaniuk
author_facet F. V. Hladkykh
N. H. Stepaniuk
author_sort F. V. Hladkykh
collection DOAJ
description Analysis of the domestic and foreign literature sources devoted to the study of pathogenetic mechanisms of gastropathy caused by non-steroidal anti-inflammatory drugs was done. Current approaches of prevention and treatment of NSAID-induced gastropathy were lined. The appropriateness of drugs with polytropic pharmacological properties (Quercetin, Vinboron and Tiotriazolin) to eliminate the side effects of NSAIDs, including ultserogenesis was discusses.
format Article
id doaj-art-253c2c6033a04b01a03885e12e70e1eb
institution OA Journals
issn 2306-4145
2310-1210
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publishDate 2014-04-01
publisher Zaporizhzhia State Medical and Pharmaceutical University
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spelling doaj-art-253c2c6033a04b01a03885e12e70e1eb2025-08-20T01:58:52ZengZaporizhzhia State Medical and Pharmaceutical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102014-04-012828610.14739/2310-1210.2014.2.25437New approaches to reduce ulcerogenity of nonsteroidal anti-inflammatory drugs: achievements, unsolved issues and ways to optimizeF. V. HladkykhN. H. StepaniukAnalysis of the domestic and foreign literature sources devoted to the study of pathogenetic mechanisms of gastropathy caused by non-steroidal anti-inflammatory drugs was done. Current approaches of prevention and treatment of NSAID-induced gastropathy were lined. The appropriateness of drugs with polytropic pharmacological properties (Quercetin, Vinboron and Tiotriazolin) to eliminate the side effects of NSAIDs, including ultserogenesis was discusses.http://zmj.zsmu.edu.ua/article/view/25437/22932NSAID-induced gastropathyIbuprofenVinboronQuercetin
spellingShingle F. V. Hladkykh
N. H. Stepaniuk
New approaches to reduce ulcerogenity of nonsteroidal anti-inflammatory drugs: achievements, unsolved issues and ways to optimize
Zaporožskij Medicinskij Žurnal
NSAID-induced gastropathy
Ibuprofen
Vinboron
Quercetin
title New approaches to reduce ulcerogenity of nonsteroidal anti-inflammatory drugs: achievements, unsolved issues and ways to optimize
title_full New approaches to reduce ulcerogenity of nonsteroidal anti-inflammatory drugs: achievements, unsolved issues and ways to optimize
title_fullStr New approaches to reduce ulcerogenity of nonsteroidal anti-inflammatory drugs: achievements, unsolved issues and ways to optimize
title_full_unstemmed New approaches to reduce ulcerogenity of nonsteroidal anti-inflammatory drugs: achievements, unsolved issues and ways to optimize
title_short New approaches to reduce ulcerogenity of nonsteroidal anti-inflammatory drugs: achievements, unsolved issues and ways to optimize
title_sort new approaches to reduce ulcerogenity of nonsteroidal anti inflammatory drugs achievements unsolved issues and ways to optimize
topic NSAID-induced gastropathy
Ibuprofen
Vinboron
Quercetin
url http://zmj.zsmu.edu.ua/article/view/25437/22932
work_keys_str_mv AT fvhladkykh newapproachestoreduceulcerogenityofnonsteroidalantiinflammatorydrugsachievementsunsolvedissuesandwaystooptimize
AT nhstepaniuk newapproachestoreduceulcerogenityofnonsteroidalantiinflammatorydrugsachievementsunsolvedissuesandwaystooptimize