Traditional Chinese acupuncture versus minimal acupuncture for mild-to-moderate knee osteoarthritis: a protocol for a randomised, controlled pilot trial
Introduction Knee osteoarthritis (KOA) is one of the most common musculoskeletal disorders. Acupuncture is a popular form of complementary medicine for musculoskeletal conditions, although the evidence is inconclusive. Our objective is to evaluate the efficacy of traditional Chinese acupuncture for...
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BMJ Publishing Group
2016-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/6/12/e013830.full |
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| author | Guang-Xia Shi Cun-Zhi Liu Ning Sun Yi Du Jian-Feng Tu Yong-Ting Li Li-Wen Zhang Yan Cao Jing-Jie Zhao Da-Chang Xiong Hai-Kun Hou |
| author_facet | Guang-Xia Shi Cun-Zhi Liu Ning Sun Yi Du Jian-Feng Tu Yong-Ting Li Li-Wen Zhang Yan Cao Jing-Jie Zhao Da-Chang Xiong Hai-Kun Hou |
| author_sort | Guang-Xia Shi |
| collection | DOAJ |
| description | Introduction Knee osteoarthritis (KOA) is one of the most common musculoskeletal disorders. Acupuncture is a popular form of complementary medicine for musculoskeletal conditions, although the evidence is inconclusive. Our objective is to evaluate the efficacy of traditional Chinese acupuncture for pain relief and function improvement in mild-to-moderate knee osteoarthritis (TCAKOA) participants.Methods/analysis 42 patients will be recruited who have been diagnosed with mild-to-moderate KOA and randomly allocated in equal proportions to traditional Chinese acupuncture or minimal acupuncture. They will receive acupuncture for 24 sessions over 8 weeks. The primary end point is success rate, which will be calculated according to a change from baseline in Western Ontario and McMaster Universities Osteoarthritis Index pain and function scores at 8 weeks. Secondary end points include pain and function measurement, global change, the quality of life and the use of non-steroidal anti-inflammatory drugs (Celebrex, Pfizer) at 8, 16 and 26 weeks.Ethics and dissemination Ethical approval of this study has been granted by the Research Ethical Committee of Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University (permission number: 2016BL-010-02). Written informed consent will be obtained from all participants. Outcomes of the trial will be disseminated through peer-reviewed publications.Trial registration number ISRCTN14016893; Pre-results. |
| format | Article |
| id | doaj-art-253b0a7dbeec48cfa5489193fc23d23f |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-253b0a7dbeec48cfa5489193fc23d23f2025-02-04T01:10:09ZengBMJ Publishing GroupBMJ Open2044-60552016-12-0161210.1136/bmjopen-2016-013830Traditional Chinese acupuncture versus minimal acupuncture for mild-to-moderate knee osteoarthritis: a protocol for a randomised, controlled pilot trialGuang-Xia Shi0Cun-Zhi Liu1Ning Sun2Yi Du3Jian-Feng Tu4Yong-Ting Li5Li-Wen Zhang6Yan Cao7Jing-Jie Zhao8Da-Chang Xiong9Hai-Kun Hou10School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China1 International Acupuncture and Moxibustion Innovation Institute, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, ChinaAcupuncture and Tuina School/The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China1 International Acupuncture and Moxibustion Innovation Institute, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China1Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, Beijing, ChinaDepartment of Dermatovenereology, Chengdu Second People’s Hospital, Chengdu, Sichuan, China6 School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China3Department of Traditional Chinese Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, China4Department of Acupuncture and Moxibustion, Beijing Jishuitan Hospital, Peking University, Beijing, China4Department of Acupuncture and Moxibustion, Beijing Jishuitan Hospital, Peking University, Beijing, ChinaIntroduction Knee osteoarthritis (KOA) is one of the most common musculoskeletal disorders. Acupuncture is a popular form of complementary medicine for musculoskeletal conditions, although the evidence is inconclusive. Our objective is to evaluate the efficacy of traditional Chinese acupuncture for pain relief and function improvement in mild-to-moderate knee osteoarthritis (TCAKOA) participants.Methods/analysis 42 patients will be recruited who have been diagnosed with mild-to-moderate KOA and randomly allocated in equal proportions to traditional Chinese acupuncture or minimal acupuncture. They will receive acupuncture for 24 sessions over 8 weeks. The primary end point is success rate, which will be calculated according to a change from baseline in Western Ontario and McMaster Universities Osteoarthritis Index pain and function scores at 8 weeks. Secondary end points include pain and function measurement, global change, the quality of life and the use of non-steroidal anti-inflammatory drugs (Celebrex, Pfizer) at 8, 16 and 26 weeks.Ethics and dissemination Ethical approval of this study has been granted by the Research Ethical Committee of Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University (permission number: 2016BL-010-02). Written informed consent will be obtained from all participants. Outcomes of the trial will be disseminated through peer-reviewed publications.Trial registration number ISRCTN14016893; Pre-results.https://bmjopen.bmj.com/content/6/12/e013830.full |
| spellingShingle | Guang-Xia Shi Cun-Zhi Liu Ning Sun Yi Du Jian-Feng Tu Yong-Ting Li Li-Wen Zhang Yan Cao Jing-Jie Zhao Da-Chang Xiong Hai-Kun Hou Traditional Chinese acupuncture versus minimal acupuncture for mild-to-moderate knee osteoarthritis: a protocol for a randomised, controlled pilot trial BMJ Open |
| title | Traditional Chinese acupuncture versus minimal acupuncture for mild-to-moderate knee osteoarthritis: a protocol for a randomised, controlled pilot trial |
| title_full | Traditional Chinese acupuncture versus minimal acupuncture for mild-to-moderate knee osteoarthritis: a protocol for a randomised, controlled pilot trial |
| title_fullStr | Traditional Chinese acupuncture versus minimal acupuncture for mild-to-moderate knee osteoarthritis: a protocol for a randomised, controlled pilot trial |
| title_full_unstemmed | Traditional Chinese acupuncture versus minimal acupuncture for mild-to-moderate knee osteoarthritis: a protocol for a randomised, controlled pilot trial |
| title_short | Traditional Chinese acupuncture versus minimal acupuncture for mild-to-moderate knee osteoarthritis: a protocol for a randomised, controlled pilot trial |
| title_sort | traditional chinese acupuncture versus minimal acupuncture for mild to moderate knee osteoarthritis a protocol for a randomised controlled pilot trial |
| url | https://bmjopen.bmj.com/content/6/12/e013830.full |
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