Risk of fatal and non-fatal cardiovascular events in men aged 25-44 in the city of Novosibirsk. Cohort study
Aim. To study the incidence and risk factors of cardiovascular events (CVEs) during an 8-year follow-up of a cohort of men aged 25-44 years (Novosibirsk).Material and methods. The cohort study included 1415 people aged 37,33 [31,83; 41,92] years (Median, Me [interquartile range, Q25; Q75], of which...
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«SILICEA-POLIGRAF» LLC
2023-02-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/3393 |
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| author | E. V. Stryukova L. V. Shcherbakova V. V. Gafarov O. D. Rymar A. D. Khudyakova N. E. Evdokimova Yu. I. Ragino |
| author_facet | E. V. Stryukova L. V. Shcherbakova V. V. Gafarov O. D. Rymar A. D. Khudyakova N. E. Evdokimova Yu. I. Ragino |
| author_sort | E. V. Stryukova |
| collection | DOAJ |
| description | Aim. To study the incidence and risk factors of cardiovascular events (CVEs) during an 8-year follow-up of a cohort of men aged 25-44 years (Novosibirsk).Material and methods. The cohort study included 1415 people aged 37,33 [31,83; 41,92] years (Median, Me [interquartile range, Q25; Q75], of which 670 (47,3%) were men. Median follow-up period was 6,9 [5,8; 7,8] years. CVEs were identified using the "Registry of Acute Myocardial Infarction", fatal cases — from the "Medical Certificates of Cause of Death". The examination program included a questionnaire, anthropometry, biochemical studies. Statistical processing was carried out using SPSS (version 13.0).Results. Thirteen CVEs were identified, of which 6 were fatal. Survival prognosis was more favorable in men without hypertension, with a heart rate (HR) <80 bpm. The risk of CVEs increased by 14% with an increase in fasting plasma glucose by 0,5 mmol/l, by 1,8 times with creatinine increase by 10 pmol/l (decreased by 29% with an increase in glomerular filtration rate by 5 ml/min /1,73 m2); 2 times with a heart rate increase by 10 bpm, regardless of other cardiometabolic risk factors.Conclusion. Significant risk factors for fatal and non-fatal CVEs in men aged 25-44 years are hypertension, heart rate >80 bpm, increased fasting plasma glucose, creatinine levels (or decreased glomerular filtration rate). |
| format | Article |
| id | doaj-art-252f887c577d47c7b5290c72dea89d4d |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2023-02-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
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| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-252f887c577d47c7b5290c72dea89d4d2025-08-20T03:18:46Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252023-02-0122110.15829/1728-8800-2023-33932631Risk of fatal and non-fatal cardiovascular events in men aged 25-44 in the city of Novosibirsk. Cohort studyE. V. Stryukova0L. V. Shcherbakova1V. V. Gafarov2O. D. Rymar3A. D. Khudyakova4N. E. Evdokimova5Yu. I. Ragino6Research Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and GeneticsResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and GeneticsResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and GeneticsResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and GeneticsResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and GeneticsResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and GeneticsResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and GeneticsAim. To study the incidence and risk factors of cardiovascular events (CVEs) during an 8-year follow-up of a cohort of men aged 25-44 years (Novosibirsk).Material and methods. The cohort study included 1415 people aged 37,33 [31,83; 41,92] years (Median, Me [interquartile range, Q25; Q75], of which 670 (47,3%) were men. Median follow-up period was 6,9 [5,8; 7,8] years. CVEs were identified using the "Registry of Acute Myocardial Infarction", fatal cases — from the "Medical Certificates of Cause of Death". The examination program included a questionnaire, anthropometry, biochemical studies. Statistical processing was carried out using SPSS (version 13.0).Results. Thirteen CVEs were identified, of which 6 were fatal. Survival prognosis was more favorable in men without hypertension, with a heart rate (HR) <80 bpm. The risk of CVEs increased by 14% with an increase in fasting plasma glucose by 0,5 mmol/l, by 1,8 times with creatinine increase by 10 pmol/l (decreased by 29% with an increase in glomerular filtration rate by 5 ml/min /1,73 m2); 2 times with a heart rate increase by 10 bpm, regardless of other cardiometabolic risk factors.Conclusion. Significant risk factors for fatal and non-fatal CVEs in men aged 25-44 years are hypertension, heart rate >80 bpm, increased fasting plasma glucose, creatinine levels (or decreased glomerular filtration rate).https://cardiovascular.elpub.ru/jour/article/view/3393cohort studycardiovascular eventshypertensionheart rateblood glucosecreatinine |
| spellingShingle | E. V. Stryukova L. V. Shcherbakova V. V. Gafarov O. D. Rymar A. D. Khudyakova N. E. Evdokimova Yu. I. Ragino Risk of fatal and non-fatal cardiovascular events in men aged 25-44 in the city of Novosibirsk. Cohort study Кардиоваскулярная терапия и профилактика cohort study cardiovascular events hypertension heart rate blood glucose creatinine |
| title | Risk of fatal and non-fatal cardiovascular events in men aged 25-44 in the city of Novosibirsk. Cohort study |
| title_full | Risk of fatal and non-fatal cardiovascular events in men aged 25-44 in the city of Novosibirsk. Cohort study |
| title_fullStr | Risk of fatal and non-fatal cardiovascular events in men aged 25-44 in the city of Novosibirsk. Cohort study |
| title_full_unstemmed | Risk of fatal and non-fatal cardiovascular events in men aged 25-44 in the city of Novosibirsk. Cohort study |
| title_short | Risk of fatal and non-fatal cardiovascular events in men aged 25-44 in the city of Novosibirsk. Cohort study |
| title_sort | risk of fatal and non fatal cardiovascular events in men aged 25 44 in the city of novosibirsk cohort study |
| topic | cohort study cardiovascular events hypertension heart rate blood glucose creatinine |
| url | https://cardiovascular.elpub.ru/jour/article/view/3393 |
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