Intestinal inflammation and microbiota modulation impact cochlear function: emerging insights in gut-ear axis

Intestinal inflammation and microbiota modulation impact cochlear function: emerging insights in gut-ear axis

Abstract Background Although several evidence demonstrates a “gut–microbiota–brain axis”, suggesting a bidirectional communication between gut microbiota and the central nervous system, less is known about a possible link between the gut and the peripheral nervous system, including the inner ear. Me...

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Main Authors: Anna Pisani, Valentina Petito, Fabiola Paciello, Valeria Emoli, Letizia Masi, Veronica Mohamed Hizam, Pierluigi Puca, Raffaele Montuoro, Federica Del Chierico, Lorenza Putignani, Claudio Grassi, Jacopo Galli, Maurizio Taglialatela, Maria Emiliana Caristo, Gianluca Ianiro, Loris Riccardo Lopetuso, Giovanni Cammarota, Antonio Gasbarrini, Anna Rita Fetoni, Franco Scaldaferri
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cell Communication and Signaling
Subjects:
Cochlea
Gut dysbiosis
Gut microbiota
Inflammation
Online Access:https://doi.org/10.1186/s12964-025-02338-1
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