Systematic Review on Treatment and Outcomes of Tuberculous Peritonitis in Patients on Peritoneal Dialysis
Introduction: Peritoneal dialysis (PD)-associated peritonitis due to tuberculosis (TB) is associated with poor outcomes and optimal treatment strategies for this condition remain unknown. Our study aimed to: (i) systematically review the published literature on peritonitis caused by Mycobacterium tu...
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| Language: | English |
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Elsevier
2024-02-01
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| Series: | Kidney International Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468024923016005 |
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| author | Chau Wei Ling Kamal Sud Ronald L. Castelino David W. Johnson Trevor H.Y. Tan Vincent W. Lee |
| author_facet | Chau Wei Ling Kamal Sud Ronald L. Castelino David W. Johnson Trevor H.Y. Tan Vincent W. Lee |
| author_sort | Chau Wei Ling |
| collection | DOAJ |
| description | Introduction: Peritoneal dialysis (PD)-associated peritonitis due to tuberculosis (TB) is associated with poor outcomes and optimal treatment strategies for this condition remain unknown. Our study aimed to: (i) systematically review the published literature on peritonitis caused by Mycobacterium tuberculosis in patients on PD and (ii) review cases of peritonitis due to M tuberculosis in patients on PD reported in Australia and New Zealand to determine the epidemiology, management strategies, and outcomes of this condition. Methods: A literature search of Medline, Scopus, Embase, ClinicalTrials.gov, Cochrane CENTRAL Register of Controlled Trials and Google Scholar for articles published from inception date to June 2022 was conducted. To be eligible, articles had to describe patient characteristics, initial anti-TB therapy, and treatment outcomes in all patients on PD with peritonitis caused by M tuberculosis. Data from the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry of patients on PD who developed peritonitis due to M tuberculosis between September 2001 and December 2020 were included and analyzed. Results: The systematic literature review identified 70 case studies (151 patients) and 8 cohort studies (97 patients), whereas the ANZDATA Registry identified 17 cases of peritonitis due to M tuberculosis. Overall, in patients diagnosed with peritonitis due to M tuberculosis, the rates of PD catheter removal and permanent transfer to hemodialysis (HD) were numerically higher in the ANZDATA Registry cases (82%) than in the case studies (23%) and cohort studies (20%). Observed all-cause mortality rates were also higher as observed in the case studies (33%) and cohort studies (26%) than in the ANZDATA Registry cases (6%). Conclusion: Tuberculous peritonitis is uncommon in patients on PD and is associated with poor outcomes. Prospective studies are warranted to study the effect of retaining PD catheters after M tuberculosis infection on patient outcomes. |
| format | Article |
| id | doaj-art-252bf436ace0481ba68473dc6f8678c7 |
| institution | OA Journals |
| issn | 2468-0249 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Kidney International Reports |
| spelling | doaj-art-252bf436ace0481ba68473dc6f8678c72025-08-20T02:05:49ZengElsevierKidney International Reports2468-02492024-02-019227728610.1016/j.ekir.2023.11.012Systematic Review on Treatment and Outcomes of Tuberculous Peritonitis in Patients on Peritoneal DialysisChau Wei Ling0Kamal Sud1Ronald L. Castelino2David W. Johnson3Trevor H.Y. Tan4Vincent W. Lee5Faculty of Medicine and Health, The University of Sydney, New South Wales, AustraliaNepean Kidney Research Centre, Department of Renal Medicine, Nepean Hospital, Sydney, New South Wales, Australia; Peritoneal Dialysis Unit, Regional Dialysis Centre, Blacktown Hospital, Sydney, New South Wales, Australia; Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry Peritoneal Dialysis Working Group, Adelaide, South AustraliaFaculty of Medicine and Health, The University of Sydney, New South Wales, Australia; Department of Pharmacy, Blacktown Hospital, Blacktown, New South Wales, AustraliaAustralia and New Zealand Dialysis and Transplant (ANZDATA) Registry Peritoneal Dialysis Working Group, Adelaide, South Australia; Australasian Kidney Trials Network, University of Queensland, Brisbane, Australia; Department of Kidney and Transplant Services, Princess Alexandra Hospital, Brisbane, Australia; Translational Research Institute, Brisbane, AustraliaNational Centre for Infectious Diseases, SingaporeDepartment of Renal Medicine, Westmead Hospital, New South Wales, Australia; Westmead Applied Research Centre, Faculty of Medicine and Health, The University of Sydney, Australia; Centre for Kidney Research, School of Public Health, The University of Sydney, New South Wales, Australia; Correspondence: Vincent W. Lee, Department of Renal Medicine, Westmead Hospital, Faculty of Medicine and Health, Westmead Applied Research Centre, New South Wales 2006 Australia.Introduction: Peritoneal dialysis (PD)-associated peritonitis due to tuberculosis (TB) is associated with poor outcomes and optimal treatment strategies for this condition remain unknown. Our study aimed to: (i) systematically review the published literature on peritonitis caused by Mycobacterium tuberculosis in patients on PD and (ii) review cases of peritonitis due to M tuberculosis in patients on PD reported in Australia and New Zealand to determine the epidemiology, management strategies, and outcomes of this condition. Methods: A literature search of Medline, Scopus, Embase, ClinicalTrials.gov, Cochrane CENTRAL Register of Controlled Trials and Google Scholar for articles published from inception date to June 2022 was conducted. To be eligible, articles had to describe patient characteristics, initial anti-TB therapy, and treatment outcomes in all patients on PD with peritonitis caused by M tuberculosis. Data from the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry of patients on PD who developed peritonitis due to M tuberculosis between September 2001 and December 2020 were included and analyzed. Results: The systematic literature review identified 70 case studies (151 patients) and 8 cohort studies (97 patients), whereas the ANZDATA Registry identified 17 cases of peritonitis due to M tuberculosis. Overall, in patients diagnosed with peritonitis due to M tuberculosis, the rates of PD catheter removal and permanent transfer to hemodialysis (HD) were numerically higher in the ANZDATA Registry cases (82%) than in the case studies (23%) and cohort studies (20%). Observed all-cause mortality rates were also higher as observed in the case studies (33%) and cohort studies (26%) than in the ANZDATA Registry cases (6%). Conclusion: Tuberculous peritonitis is uncommon in patients on PD and is associated with poor outcomes. Prospective studies are warranted to study the effect of retaining PD catheters after M tuberculosis infection on patient outcomes.http://www.sciencedirect.com/science/article/pii/S2468024923016005antituberculosis regimenMycobacterium tuberculosisoutcomesperitoneal dialysisperitonitistreatment |
| spellingShingle | Chau Wei Ling Kamal Sud Ronald L. Castelino David W. Johnson Trevor H.Y. Tan Vincent W. Lee Systematic Review on Treatment and Outcomes of Tuberculous Peritonitis in Patients on Peritoneal Dialysis Kidney International Reports antituberculosis regimen Mycobacterium tuberculosis outcomes peritoneal dialysis peritonitis treatment |
| title | Systematic Review on Treatment and Outcomes of Tuberculous Peritonitis in Patients on Peritoneal Dialysis |
| title_full | Systematic Review on Treatment and Outcomes of Tuberculous Peritonitis in Patients on Peritoneal Dialysis |
| title_fullStr | Systematic Review on Treatment and Outcomes of Tuberculous Peritonitis in Patients on Peritoneal Dialysis |
| title_full_unstemmed | Systematic Review on Treatment and Outcomes of Tuberculous Peritonitis in Patients on Peritoneal Dialysis |
| title_short | Systematic Review on Treatment and Outcomes of Tuberculous Peritonitis in Patients on Peritoneal Dialysis |
| title_sort | systematic review on treatment and outcomes of tuberculous peritonitis in patients on peritoneal dialysis |
| topic | antituberculosis regimen Mycobacterium tuberculosis outcomes peritoneal dialysis peritonitis treatment |
| url | http://www.sciencedirect.com/science/article/pii/S2468024923016005 |
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