Comparing the Use of Transverse Abdominis Plane Block and Splash Block for Postoperative Pain Control in Dogs Undergoing Mastectomy—A Blinded Randomized Prospective Clinical Study
To compare the use of postoperative analgesia for mastectomy, 44 dogs were randomly allocated to either the Splash treatment group (group A) or the Transverse Abdominis Plane block treatment group (TAP, group B). Following intramuscular (IM) premedication with pethidine (4 mg kg<sup>−1</sup...
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2025-05-01
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| author | Daniele Corona Simone K. Ringer Stefanie Keller Iris M. Reichler Regula Bettschart-Wolfensberger Annette P. N. Kutter |
| author_facet | Daniele Corona Simone K. Ringer Stefanie Keller Iris M. Reichler Regula Bettschart-Wolfensberger Annette P. N. Kutter |
| author_sort | Daniele Corona |
| collection | DOAJ |
| description | To compare the use of postoperative analgesia for mastectomy, 44 dogs were randomly allocated to either the Splash treatment group (group A) or the Transverse Abdominis Plane block treatment group (TAP, group B). Following intramuscular (IM) premedication with pethidine (4 mg kg<sup>−1</sup>) and acepromazine (0.01 mg kg<sup>−1</sup>), anesthesia was induced with intravenous (IV) propofol and maintained with isoflurane by an anesthetist (DC) who was unaware of the treatment. In group A, ropivacaine 0.5% (2 mg kg<sup>−1</sup>) was administered prior to surgical wound closure. In group B, ropivacaine 0.5% (0.8–1 mg kg<sup>−1</sup> per point) was administered by ultrasound-guided TAP block with two injection points per treated body side. At the end of the surgery, all dogs received pethidine (4 mg kg<sup>−1</sup> IM), meloxicam (0.2 mg kg<sup>−1</sup> IV), and acepromazine (0.005 mg kg<sup>−1</sup> IV). The animals’ pain was assessed by the anesthetist, who remained unaware of the treatment type used, via the Short Form of the Glasgow Composite Pain Scale. When the pain scores were ≥6, methadone (0.2 mg kg<sup>−1</sup> IV) and gabapentin (10 mg kg<sup>−1</sup> per oral) were started. When the pain score remained ≥ 6, ketamine (1 mg kg<sup>−1</sup> subcutaneously) was administered. The dogs in the TAP block group had lower postoperative pain scores 3–12 h after anesthesia administration was terminated and required significantly less rescue analgesia. |
| format | Article |
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| institution | Kabale University |
| issn | 2076-2615 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
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| series | Animals |
| spelling | doaj-art-25251e6ac058415fb90d5b364e7119122025-08-20T03:52:57ZengMDPI AGAnimals2076-26152025-05-01159132310.3390/ani15091323Comparing the Use of Transverse Abdominis Plane Block and Splash Block for Postoperative Pain Control in Dogs Undergoing Mastectomy—A Blinded Randomized Prospective Clinical StudyDaniele Corona0Simone K. Ringer1Stefanie Keller2Iris M. Reichler3Regula Bettschart-Wolfensberger4Annette P. N. Kutter5Department of Clinical Diagnostics and Services, Section of Anaesthesiology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandDepartment of Clinical Diagnostics and Services, Section of Anaesthesiology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandClinic for Animal Reproduction Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandClinic for Animal Reproduction Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandDepartment of Clinical Diagnostics and Services, Section of Anaesthesiology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandDepartment of Clinical Diagnostics and Services, Section of Anaesthesiology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, SwitzerlandTo compare the use of postoperative analgesia for mastectomy, 44 dogs were randomly allocated to either the Splash treatment group (group A) or the Transverse Abdominis Plane block treatment group (TAP, group B). Following intramuscular (IM) premedication with pethidine (4 mg kg<sup>−1</sup>) and acepromazine (0.01 mg kg<sup>−1</sup>), anesthesia was induced with intravenous (IV) propofol and maintained with isoflurane by an anesthetist (DC) who was unaware of the treatment. In group A, ropivacaine 0.5% (2 mg kg<sup>−1</sup>) was administered prior to surgical wound closure. In group B, ropivacaine 0.5% (0.8–1 mg kg<sup>−1</sup> per point) was administered by ultrasound-guided TAP block with two injection points per treated body side. At the end of the surgery, all dogs received pethidine (4 mg kg<sup>−1</sup> IM), meloxicam (0.2 mg kg<sup>−1</sup> IV), and acepromazine (0.005 mg kg<sup>−1</sup> IV). The animals’ pain was assessed by the anesthetist, who remained unaware of the treatment type used, via the Short Form of the Glasgow Composite Pain Scale. When the pain scores were ≥6, methadone (0.2 mg kg<sup>−1</sup> IV) and gabapentin (10 mg kg<sup>−1</sup> per oral) were started. When the pain score remained ≥ 6, ketamine (1 mg kg<sup>−1</sup> subcutaneously) was administered. The dogs in the TAP block group had lower postoperative pain scores 3–12 h after anesthesia administration was terminated and required significantly less rescue analgesia.https://www.mdpi.com/2076-2615/15/9/1323neoplasiamammary tumorcaninelocoregional anesthesiapain score |
| spellingShingle | Daniele Corona Simone K. Ringer Stefanie Keller Iris M. Reichler Regula Bettschart-Wolfensberger Annette P. N. Kutter Comparing the Use of Transverse Abdominis Plane Block and Splash Block for Postoperative Pain Control in Dogs Undergoing Mastectomy—A Blinded Randomized Prospective Clinical Study Animals neoplasia mammary tumor canine locoregional anesthesia pain score |
| title | Comparing the Use of Transverse Abdominis Plane Block and Splash Block for Postoperative Pain Control in Dogs Undergoing Mastectomy—A Blinded Randomized Prospective Clinical Study |
| title_full | Comparing the Use of Transverse Abdominis Plane Block and Splash Block for Postoperative Pain Control in Dogs Undergoing Mastectomy—A Blinded Randomized Prospective Clinical Study |
| title_fullStr | Comparing the Use of Transverse Abdominis Plane Block and Splash Block for Postoperative Pain Control in Dogs Undergoing Mastectomy—A Blinded Randomized Prospective Clinical Study |
| title_full_unstemmed | Comparing the Use of Transverse Abdominis Plane Block and Splash Block for Postoperative Pain Control in Dogs Undergoing Mastectomy—A Blinded Randomized Prospective Clinical Study |
| title_short | Comparing the Use of Transverse Abdominis Plane Block and Splash Block for Postoperative Pain Control in Dogs Undergoing Mastectomy—A Blinded Randomized Prospective Clinical Study |
| title_sort | comparing the use of transverse abdominis plane block and splash block for postoperative pain control in dogs undergoing mastectomy a blinded randomized prospective clinical study |
| topic | neoplasia mammary tumor canine locoregional anesthesia pain score |
| url | https://www.mdpi.com/2076-2615/15/9/1323 |
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