MicroRNAs in circulating extracellular vesicles as biomarkers of early colorectal cancer captured using high mannose N-glycan-specific lectin from Oscillatoria Agardhii

MicroRNAs in circulating extracellular vesicles as biomarkers of early colorectal cancer captured using high mannose N-glycan-specific lectin from Oscillatoria Agardhii

IntroductionLectin (OAA), isolated from the filamentous cyanobacterium Oscillatoria agardhii, exhibits high specificity and strong binding affinity for high-mannose (HM) N-glycans. Previous studies have demonstrated that OAA captured extracellular vesicles (EVs) derived from cancer cell lines. This...

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Bibliographic Details
Main Authors: Sanae Nakayama, Miyabi Umeda, Kenya Kobayashi, Yukiko Nakano, Kanji Hori, Tsukuru Umemura, Hiroshi Kurokawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
OAA
lectin
high-mannose type N-linked glycan
extracellular vesicle
miRNA
colorectal cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1619460/full
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