Laparoscopic-Assisted Removal of Bleeding Mesenteric Meckel’s Diverticulum in Children: Case Series and Systematic Review

<b>Background:</b> Meckel’s diverticulum on the mesenteric side has been reported only as case reports in the literature and presents a diagnostic challenge, with ultimate recognition often taking place intraoperatively. We describe a case series of children with mesenteric Meckel’s dive...

Full description

Saved in:
Bibliographic Details
Main Authors: Veronica Vitali, Giulia Fusi, Alessandro Raffaele, Maria Ruffoli, Simonetta Mencherini, Carmine Noviello, Gian Battista Parigi, Mirko Bertozzi
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Gastrointestinal Disorders
Subjects:
Online Access:https://www.mdpi.com/2624-5647/7/1/24
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850204759382818816
author Veronica Vitali
Giulia Fusi
Alessandro Raffaele
Maria Ruffoli
Simonetta Mencherini
Carmine Noviello
Gian Battista Parigi
Mirko Bertozzi
author_facet Veronica Vitali
Giulia Fusi
Alessandro Raffaele
Maria Ruffoli
Simonetta Mencherini
Carmine Noviello
Gian Battista Parigi
Mirko Bertozzi
author_sort Veronica Vitali
collection DOAJ
description <b>Background:</b> Meckel’s diverticulum on the mesenteric side has been reported only as case reports in the literature and presents a diagnostic challenge, with ultimate recognition often taking place intraoperatively. We describe a case series of children with mesenteric Meckel’s diverticulum (MMD) treated at our institution, along with the results of a systematic review of the literature. <b>Methods:</b> Our experience on MMD was analyzed along with a systematic literature review performed according to PRISMA criteria. We identified studies published from 1941 to 2023 from PubMed, EMBASE, SCOPUS, and WOS. Search terms were variations of “Meckel”, “diverticulum”, and “mesenteric”. Inclusion criteria were patients < 18 years of age and articles written in English. <b>Results:</b> A total of three cases of MMD were observed and treated in our hospital. The mean age was 7.6 years. The most common symptoms were rectal bleeding and abdominal pain. Diagnostic workup included ultrasound and both upper and lower endoscopy. Surgery was performed by the laparoscopy-assisted technique. One case had to be reoperated due to postoperative intestinal occlusion. The mean length of hospital stay was 9.3 days. The literature search yielded 795 citations; out of the 590 papers remaining after the exclusion of 205 duplications, only 15 papers matched the inclusion criteria and were included and analyzed. <b>Conclusions:</b> MMD remains a rare and elusive pathology, sharing with its normal counterpart symptoms and signs. In our experience, and in the more recent literature, laparoscopy-assisted surgery appears safe and effective both for final diagnosis and definitive treatment.
format Article
id doaj-art-250c845a37f84005a9ba24502da2e5bf
institution OA Journals
issn 2624-5647
language English
publishDate 2025-03-01
publisher MDPI AG
record_format Article
series Gastrointestinal Disorders
spelling doaj-art-250c845a37f84005a9ba24502da2e5bf2025-08-20T02:11:14ZengMDPI AGGastrointestinal Disorders2624-56472025-03-01712410.3390/gidisord7010024Laparoscopic-Assisted Removal of Bleeding Mesenteric Meckel’s Diverticulum in Children: Case Series and Systematic ReviewVeronica Vitali0Giulia Fusi1Alessandro Raffaele2Maria Ruffoli3Simonetta Mencherini4Carmine Noviello5Gian Battista Parigi6Mirko Bertozzi7Department of Pediatric Surgery, IRCCS San Matteo Polyclinic, University of Pavia, 27100 Pavia, ItalyDepartment of Pediatric Surgery, IRCCS San Matteo Polyclinic, University of Pavia, 27100 Pavia, ItalyDepartment of Pediatric Surgery, IRCCS San Matteo Polyclinic, University of Pavia, 27100 Pavia, ItalyDepartment of Pediatric Surgery, IRCCS San Matteo Polyclinic, University of Pavia, 27100 Pavia, ItalyAnesthesiology and Intensive Care Unit, Fondazione IRCCS San Matteo Polyclinic, 27100 Pavia, ItalyPediatric Surgery Unit, Department of Woman, Child, General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, 81100 Naples, ItalyDepartment of Pediatric Surgery, IRCCS San Matteo Polyclinic, University of Pavia, 27100 Pavia, ItalyDepartment of Pediatric Surgery, IRCCS San Matteo Polyclinic, University of Pavia, 27100 Pavia, Italy<b>Background:</b> Meckel’s diverticulum on the mesenteric side has been reported only as case reports in the literature and presents a diagnostic challenge, with ultimate recognition often taking place intraoperatively. We describe a case series of children with mesenteric Meckel’s diverticulum (MMD) treated at our institution, along with the results of a systematic review of the literature. <b>Methods:</b> Our experience on MMD was analyzed along with a systematic literature review performed according to PRISMA criteria. We identified studies published from 1941 to 2023 from PubMed, EMBASE, SCOPUS, and WOS. Search terms were variations of “Meckel”, “diverticulum”, and “mesenteric”. Inclusion criteria were patients < 18 years of age and articles written in English. <b>Results:</b> A total of three cases of MMD were observed and treated in our hospital. The mean age was 7.6 years. The most common symptoms were rectal bleeding and abdominal pain. Diagnostic workup included ultrasound and both upper and lower endoscopy. Surgery was performed by the laparoscopy-assisted technique. One case had to be reoperated due to postoperative intestinal occlusion. The mean length of hospital stay was 9.3 days. The literature search yielded 795 citations; out of the 590 papers remaining after the exclusion of 205 duplications, only 15 papers matched the inclusion criteria and were included and analyzed. <b>Conclusions:</b> MMD remains a rare and elusive pathology, sharing with its normal counterpart symptoms and signs. In our experience, and in the more recent literature, laparoscopy-assisted surgery appears safe and effective both for final diagnosis and definitive treatment.https://www.mdpi.com/2624-5647/7/1/24Mesenteric Meckel’s diverticulumlaparo-assisted surgerychildren
spellingShingle Veronica Vitali
Giulia Fusi
Alessandro Raffaele
Maria Ruffoli
Simonetta Mencherini
Carmine Noviello
Gian Battista Parigi
Mirko Bertozzi
Laparoscopic-Assisted Removal of Bleeding Mesenteric Meckel’s Diverticulum in Children: Case Series and Systematic Review
Gastrointestinal Disorders
Mesenteric Meckel’s diverticulum
laparo-assisted surgery
children
title Laparoscopic-Assisted Removal of Bleeding Mesenteric Meckel’s Diverticulum in Children: Case Series and Systematic Review
title_full Laparoscopic-Assisted Removal of Bleeding Mesenteric Meckel’s Diverticulum in Children: Case Series and Systematic Review
title_fullStr Laparoscopic-Assisted Removal of Bleeding Mesenteric Meckel’s Diverticulum in Children: Case Series and Systematic Review
title_full_unstemmed Laparoscopic-Assisted Removal of Bleeding Mesenteric Meckel’s Diverticulum in Children: Case Series and Systematic Review
title_short Laparoscopic-Assisted Removal of Bleeding Mesenteric Meckel’s Diverticulum in Children: Case Series and Systematic Review
title_sort laparoscopic assisted removal of bleeding mesenteric meckel s diverticulum in children case series and systematic review
topic Mesenteric Meckel’s diverticulum
laparo-assisted surgery
children
url https://www.mdpi.com/2624-5647/7/1/24
work_keys_str_mv AT veronicavitali laparoscopicassistedremovalofbleedingmesentericmeckelsdiverticuluminchildrencaseseriesandsystematicreview
AT giuliafusi laparoscopicassistedremovalofbleedingmesentericmeckelsdiverticuluminchildrencaseseriesandsystematicreview
AT alessandroraffaele laparoscopicassistedremovalofbleedingmesentericmeckelsdiverticuluminchildrencaseseriesandsystematicreview
AT mariaruffoli laparoscopicassistedremovalofbleedingmesentericmeckelsdiverticuluminchildrencaseseriesandsystematicreview
AT simonettamencherini laparoscopicassistedremovalofbleedingmesentericmeckelsdiverticuluminchildrencaseseriesandsystematicreview
AT carminenoviello laparoscopicassistedremovalofbleedingmesentericmeckelsdiverticuluminchildrencaseseriesandsystematicreview
AT gianbattistaparigi laparoscopicassistedremovalofbleedingmesentericmeckelsdiverticuluminchildrencaseseriesandsystematicreview
AT mirkobertozzi laparoscopicassistedremovalofbleedingmesentericmeckelsdiverticuluminchildrencaseseriesandsystematicreview