Metformin inhibits melanin synthesis and melanosome transfer through the cAMP pathway

Metformin inhibits melanin synthesis and melanosome transfer through the cAMP pathway

Abstract Several studies have demonstrated the inhibitory effect of metformin on pigmentation. However, the effect of metformin on melanosome transfer remains unknown. The goals of this study were to elucidate the effects of metformin on melanogenesis and melanosome transfer and explore the related...

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Bibliographic Details
Main Authors: Xing Liu, Xiaojie Sun, Yunyao Liu, Wenzhu Wang, Hedan Yang, Yiping Ge, Yin Yang, Xu Chen, Tong Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Metformin
Melanogenesis
Melanosome transfer
cAMP
Online Access:https://doi.org/10.1038/s41598-025-95245-x
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