Vitrification affects the post-implantation development of mouse embryos by inducing DNA damage and epigenetic modifications

Vitrification affects the post-implantation development of mouse embryos by inducing DNA damage and epigenetic modifications

Abstract Vitrification is widely used in assisted reproductive technology (ART) for female infertility, but the long-term effect on the embryo of vitrification has not been comprehensively studied. The study aimed to investigate the effect of vitrification on long-term development of mouse embryos....

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Bibliographic Details
Main Authors: Yurong Chen, Haibo Zhu, Fucheng Guo, Luyao Wang, Wenli Zhang, Ruizhi Liu, Xiaoling Zhang, Xiangpeng Dai
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Clinical Epigenetics
Subjects:
Vitrification
DNA damage
Epigenetic modification
ROS
Embryo development
Mitochondria
Online Access:https://doi.org/10.1186/s13148-025-01826-y
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