Potential active ingredients and mechanisms of Shufeitie ointment in the treatment of chronic obstructive pulmonary disease by integrating transdermal chemistry and network pharmacology

Potential active ingredients and mechanisms of Shufeitie ointment in the treatment of chronic obstructive pulmonary disease by integrating transdermal chemistry and network pharmacology

PurposeThis study aims to identify the transdermal penetration components of Shufeitie ointment (SFTOT) and investigate the potential active components and mechanisms through which SFTOT exerts its effects on Chronic Obstructive Pulmonary Disease (COPD).MethodsAn in vitro permeation test (IVPT) of S...

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Bibliographic Details
Main Authors: Jianing Sun, Di Zhang, Panpan Wang, Junhan Shi, Tan Xue, Panpan Zhang, Qi Wang, Xinjing Gui, Suyun Li, Jiansheng Li, Xuelin Li, Ruixin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
Subjects:
Shufeitie ointment
chronic obstructive pulmonary disease
UHPLC-Q-orbitrap/MS
external preparations
Franz diffusion cell
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1605372/full
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