Age-related changes in myelin and myelin water quantified with short-TR adiabatic inversion-recovery (STAIR) sequences

Age-related changes in myelin and myelin water quantified with short-TR adiabatic inversion-recovery (STAIR) sequences

Myelin proton density fraction (MPDF) and myelin water fraction (MWF) measured with short-TR adiabatic inversion-recovery (STAIR) sequences are potential biomarkers of aging and neurodegeneration, but the effects of aging on MPDF/MWF remain unknown. This study aims to assess relationships between ag...

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Bibliographic Details
Main Authors: James Lo, Jiaji Wang, Dylan Tran, Gabrielle Nemeh, Brandon Liu, Soo Hyun Shin, Jiyo S. Athertya, Dawn Schiehser, Yajun Ma, Jiang Du
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:NeuroImage: Clinical
Subjects:
Myelin content
Myelin water
Aging
Brain
Biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158225000713
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