The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review

The cribriform-morular variant of papillary thyroid carcinoma (CMV-PTC) is now designated as morular cribriform thyroid carcinoma (CMTC) according to the 5th edition of the World Health Organization (WHO) Classification of Thyroid Tumors. CMTC can appear within a familial adenomatous polyposis (FAP)...

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Main Authors: Sucong Lyu, Guoqiang Zhong, Hui Chen, Jin Li, Mingsong Li
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2023/6222432
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author Sucong Lyu
Guoqiang Zhong
Hui Chen
Jin Li
Mingsong Li
author_facet Sucong Lyu
Guoqiang Zhong
Hui Chen
Jin Li
Mingsong Li
author_sort Sucong Lyu
collection DOAJ
description The cribriform-morular variant of papillary thyroid carcinoma (CMV-PTC) is now designated as morular cribriform thyroid carcinoma (CMTC) according to the 5th edition of the World Health Organization (WHO) Classification of Thyroid Tumors. CMTC can appear within a familial adenomatous polyposis (FAP) or be sporadic. We report the first case of a young female patient in China who was diagnosed with FAP and CMTC with a mutation in exon 16 of the APC gene underlying the disease. The main purpose of this case report is to provide a special pathological type of thyroid tumors, which is expected to be helpful for clinical work in the future.
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institution Kabale University
issn 2090-6536
language English
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-24f122a8152d4711add6eb0e01ddd57d2025-08-20T03:54:52ZengWileyCase Reports in Gastrointestinal Medicine2090-65362023-01-01202310.1155/2023/6222432The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief ReviewSucong Lyu0Guoqiang Zhong1Hui Chen2Jin Li3Mingsong Li4Department of GastroenterologyDepartment of GastroenterologyDepartment of PathologyDepartment of GastroenterologyDepartment of GastroenterologyThe cribriform-morular variant of papillary thyroid carcinoma (CMV-PTC) is now designated as morular cribriform thyroid carcinoma (CMTC) according to the 5th edition of the World Health Organization (WHO) Classification of Thyroid Tumors. CMTC can appear within a familial adenomatous polyposis (FAP) or be sporadic. We report the first case of a young female patient in China who was diagnosed with FAP and CMTC with a mutation in exon 16 of the APC gene underlying the disease. The main purpose of this case report is to provide a special pathological type of thyroid tumors, which is expected to be helpful for clinical work in the future.http://dx.doi.org/10.1155/2023/6222432
spellingShingle Sucong Lyu
Guoqiang Zhong
Hui Chen
Jin Li
Mingsong Li
The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
Case Reports in Gastrointestinal Medicine
title The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title_full The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title_fullStr The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title_full_unstemmed The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title_short The First Case of Cribriform-Morular Thyroid Carcinoma and FAP with APC Gene Mutation in China: A Case Report and Brief Review
title_sort first case of cribriform morular thyroid carcinoma and fap with apc gene mutation in china a case report and brief review
url http://dx.doi.org/10.1155/2023/6222432
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