Inhibition of glutathione peroxidase 4 suppresses gastric cancer peritoneal metastasis via regulation of RCC2 homeostasis
Gastric cancer (GC) is one of the most lethal malignancies due to high metastatic rate, making the identification of new therapeutic targets critical for developing effective anti-GC treatments. Glutathione peroxidase 4 (GPx4), a key regulator of ferroptosis and redox homeostasis, contributes to pro...
Saved in:
Main Authors: | Can Hu, Jingli Xu, Yanqiang Zhang, Ruolan Zhang, Siwei Pan, Jiahui Chen, Yan Wang, Qianyu Zhao, Yuqi Wang, Weiwei Zhu, Mengxuan Cao, Shengjie Zhang, Dan Zu, Zhiyuan Xu, Ji Jing, Xiangdong Cheng |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-03-01
|
Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231725000321 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Correlation of ferritin and glutathione peroxidase 4 (GPX4) level as a marker of ferroptosis process in endometrioma
by: Rina Nulianti, et al.
Published: (2025-02-01) -
Mechanistic insights into 125I seed implantation therapy for Cholangiocarcinoma: focus on ROS-Mediated apoptosis and the role of GPX2
by: Jun Luo, et al.
Published: (2024-06-01) -
Loss of flavonoids homeostasis leads to pistillody in sua-CMS of Nicotiana tabacum
by: Jie Xu, et al.
Published: (2025-01-01) -
AURKB affects the proliferation of clear cell renal cell carcinoma by regulating fatty acid metabolism
by: Yang Yang, et al.
Published: (2025-01-01) -
CDC20‐Mediated Selective Autophagy Degradation of PBRM1 Affects Immunotherapy for Renal Cell Carcinoma
by: Yizeng Fan, et al.
Published: (2025-02-01)