Detecting subclinical cardiotoxicity during immune checkpoint inhibitor therapy: a combined GLS and ECG repolarization analysis

Detecting subclinical cardiotoxicity during immune checkpoint inhibitor therapy: a combined GLS and ECG repolarization analysis

PurposeImmune checkpoint inhibitors (ICIs) can induce subclinical cardiac dysfunction that often goes undetected by conventional monitoring. This study evaluated whether echocardiographic global longitudinal strain (GLS) and electrocardiographic (ECG) repolarization parameters could detect early, su...

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Bibliographic Details
Main Authors: Dogac Oksen, Muhammed Heja Gecit, Sukru Arslan, Muzaffer Aslan, Yunus Emre Yavuz, Saban Secmeler, Veysel Oktay
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
immune checkpoint inhibitors
cardiotoxicity
cardio-oncology
global longitudinal strain
repolarization abnormalities
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1615209/full
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