Gastrointestinal Bleeding Unmasking Gastric Metastases From a Primary Breast Malignancy: A Case Report
Metastases to the gastrointestinal tract from primary breast malignancies are rare. Acute gastrointestinal bleeding in patients with history of breast cancer, however, should raise clinical suspicion and warrant further investigation for metastatic disease involving the gastrointestinal tract. We re...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/crgm/2763114 |
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| _version_ | 1850277738492985344 |
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| author | Thilini Delungahawatta Richard Hum Stephanie M. Woo Rashmi Samdani Mark J. Real |
| author_facet | Thilini Delungahawatta Richard Hum Stephanie M. Woo Rashmi Samdani Mark J. Real |
| author_sort | Thilini Delungahawatta |
| collection | DOAJ |
| description | Metastases to the gastrointestinal tract from primary breast malignancies are rare. Acute gastrointestinal bleeding in patients with history of breast cancer, however, should raise clinical suspicion and warrant further investigation for metastatic disease involving the gastrointestinal tract. We report a case of a 74-year-old female with metastatic breast cancer and provoked thromboembolic events on anticoagulation, who was found to have poorly cohesive gastric carcinoma with immunohistochemistry consistent with primary breast malignancy, after presenting with new-onset melena. Use of anticoagulation may have exacerbated bleeding prompting endoscopic examination. Biopsy and histologic assessment are needed for definitive diagnosis and timely management. |
| format | Article |
| id | doaj-art-24e620b2a7fc46e99d6867156d76c2f3 |
| institution | OA Journals |
| issn | 2090-6536 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-24e620b2a7fc46e99d6867156d76c2f32025-08-20T01:49:46ZengWileyCase Reports in Gastrointestinal Medicine2090-65362025-01-01202510.1155/crgm/2763114Gastrointestinal Bleeding Unmasking Gastric Metastases From a Primary Breast Malignancy: A Case ReportThilini Delungahawatta0Richard Hum1Stephanie M. Woo2Rashmi Samdani3Mark J. Real4Department of Internal MedicineGeorgetown University School of MedicineDepartment of GastroenterologyDepartment of PathologyDepartment of GastroenterologyMetastases to the gastrointestinal tract from primary breast malignancies are rare. Acute gastrointestinal bleeding in patients with history of breast cancer, however, should raise clinical suspicion and warrant further investigation for metastatic disease involving the gastrointestinal tract. We report a case of a 74-year-old female with metastatic breast cancer and provoked thromboembolic events on anticoagulation, who was found to have poorly cohesive gastric carcinoma with immunohistochemistry consistent with primary breast malignancy, after presenting with new-onset melena. Use of anticoagulation may have exacerbated bleeding prompting endoscopic examination. Biopsy and histologic assessment are needed for definitive diagnosis and timely management.http://dx.doi.org/10.1155/crgm/2763114 |
| spellingShingle | Thilini Delungahawatta Richard Hum Stephanie M. Woo Rashmi Samdani Mark J. Real Gastrointestinal Bleeding Unmasking Gastric Metastases From a Primary Breast Malignancy: A Case Report Case Reports in Gastrointestinal Medicine |
| title | Gastrointestinal Bleeding Unmasking Gastric Metastases From a Primary Breast Malignancy: A Case Report |
| title_full | Gastrointestinal Bleeding Unmasking Gastric Metastases From a Primary Breast Malignancy: A Case Report |
| title_fullStr | Gastrointestinal Bleeding Unmasking Gastric Metastases From a Primary Breast Malignancy: A Case Report |
| title_full_unstemmed | Gastrointestinal Bleeding Unmasking Gastric Metastases From a Primary Breast Malignancy: A Case Report |
| title_short | Gastrointestinal Bleeding Unmasking Gastric Metastases From a Primary Breast Malignancy: A Case Report |
| title_sort | gastrointestinal bleeding unmasking gastric metastases from a primary breast malignancy a case report |
| url | http://dx.doi.org/10.1155/crgm/2763114 |
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