Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report

Introduction: Cefuroxime-induced toxic maculopathy can occur when an incorrect or correct dilution is injected intracamerally during cataract surgery. Case Report: An 83-year-old male developed toxic maculopathy on the first postoperative day after uneventful cataract surgery. An investig...

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Main Authors: Maria E. Pantelidou, Stylianos Bebis, Elias P. Pantelidis, Tryfon Rotsos
Format: Article
Language:English
Published: Karger Publishers 2025-01-01
Series:Case Reports in Ophthalmology
Online Access:https://karger.com/article/doi/10.1159/000543837
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author Maria E. Pantelidou
Stylianos Bebis
Elias P. Pantelidis
Tryfon Rotsos
author_facet Maria E. Pantelidou
Stylianos Bebis
Elias P. Pantelidis
Tryfon Rotsos
author_sort Maria E. Pantelidou
collection DOAJ
description Introduction: Cefuroxime-induced toxic maculopathy can occur when an incorrect or correct dilution is injected intracamerally during cataract surgery. Case Report: An 83-year-old male developed toxic maculopathy on the first postoperative day after uneventful cataract surgery. An investigation of the case confirmed that the patient developed sporadic toxic maculopathy after a standard intracameral cefuroxime dose. The patient showed complete recovery of vision during the first postoperative week. Conclusion: Cefuroxime-induced toxic maculopathy may occur sporadically and have a good visual outcome. It may be distinguished from toxic maculopathy induced by incorrect dilution based on its different clinical appearance and, in some cases, the guarded outcome. Correct dilution of cefuroxime is of utmost importance.
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issn 1663-2699
language English
publishDate 2025-01-01
publisher Karger Publishers
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series Case Reports in Ophthalmology
spelling doaj-art-24e1bdc3b46c476cb1eb473cba62d6be2025-08-20T03:09:47ZengKarger PublishersCase Reports in Ophthalmology1663-26992025-01-0116117118110.1159/000543837Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case ReportMaria E. PantelidouStylianos BebisElias P. PantelidisTryfon Rotsos Introduction: Cefuroxime-induced toxic maculopathy can occur when an incorrect or correct dilution is injected intracamerally during cataract surgery. Case Report: An 83-year-old male developed toxic maculopathy on the first postoperative day after uneventful cataract surgery. An investigation of the case confirmed that the patient developed sporadic toxic maculopathy after a standard intracameral cefuroxime dose. The patient showed complete recovery of vision during the first postoperative week. Conclusion: Cefuroxime-induced toxic maculopathy may occur sporadically and have a good visual outcome. It may be distinguished from toxic maculopathy induced by incorrect dilution based on its different clinical appearance and, in some cases, the guarded outcome. Correct dilution of cefuroxime is of utmost importance. https://karger.com/article/doi/10.1159/000543837
spellingShingle Maria E. Pantelidou
Stylianos Bebis
Elias P. Pantelidis
Tryfon Rotsos
Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report
Case Reports in Ophthalmology
title Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report
title_full Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report
title_fullStr Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report
title_full_unstemmed Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report
title_short Cefuroxime-Induced Toxic Maculopathy after Intracameral Injection of Standard Dose: A Case Report
title_sort cefuroxime induced toxic maculopathy after intracameral injection of standard dose a case report
url https://karger.com/article/doi/10.1159/000543837
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AT stylianosbebis cefuroximeinducedtoxicmaculopathyafterintracameralinjectionofstandarddoseacasereport
AT eliasppantelidis cefuroximeinducedtoxicmaculopathyafterintracameralinjectionofstandarddoseacasereport
AT tryfonrotsos cefuroximeinducedtoxicmaculopathyafterintracameralinjectionofstandarddoseacasereport