Severe Psychotic Disorder as the Main Manifestation of Adrenal Insufficiency

We describe a case of severe psychotic disorder as the only manifestation of primary adrenal insufficiency. A 63-year-old man presented with psychotic symptoms without any prior psychiatric history. During the clinical and laboratorial investigation, exams revealed a normovolemic hyponatremia. The p...

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Main Authors: Julia de Lima Farah, Carolina Villar Lauand, Lucas Chequi, Enrico Fortunato, Felipe Pasqualino, Luis Henrique Bignotto, Rafael Loch Batista, Ivan Aprahamian
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2015/512430
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author Julia de Lima Farah
Carolina Villar Lauand
Lucas Chequi
Enrico Fortunato
Felipe Pasqualino
Luis Henrique Bignotto
Rafael Loch Batista
Ivan Aprahamian
author_facet Julia de Lima Farah
Carolina Villar Lauand
Lucas Chequi
Enrico Fortunato
Felipe Pasqualino
Luis Henrique Bignotto
Rafael Loch Batista
Ivan Aprahamian
author_sort Julia de Lima Farah
collection DOAJ
description We describe a case of severe psychotic disorder as the only manifestation of primary adrenal insufficiency. A 63-year-old man presented with psychotic symptoms without any prior psychiatric history. During the clinical and laboratorial investigation, exams revealed a normovolemic hyponatremia. The patient showed no other clinical signs or symptoms compatible with adrenal insufficiency but displayed very high ACTH and low serum cortisol concentrations. Brain magnetic resonance imaging showed no significant changes, including the pituitary gland. The patient was initially treated with intravenous corticosteroids, resulting in rapid remission of the psychotic symptoms. The association between adrenal insufficiency and neuropsychiatric symptoms is rare but these symptoms can often be the first clinical presentation of the disease.
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issn 2090-682X
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series Case Reports in Psychiatry
spelling doaj-art-24d860eb4a07488e97958c095383b13d2025-02-03T05:53:00ZengWileyCase Reports in Psychiatry2090-682X2090-68382015-01-01201510.1155/2015/512430512430Severe Psychotic Disorder as the Main Manifestation of Adrenal InsufficiencyJulia de Lima Farah0Carolina Villar Lauand1Lucas Chequi2Enrico Fortunato3Felipe Pasqualino4Luis Henrique Bignotto5Rafael Loch Batista6Ivan Aprahamian7Department of Internal Medicine, Faculty of Medicine of Jundiaí, Jundiaí, BrazilDepartment of Internal Medicine, Faculty of Medicine of Jundiaí, Jundiaí, BrazilDepartment of Internal Medicine, Faculty of Medicine of Jundiaí, Jundiaí, BrazilDepartment of Internal Medicine, Faculty of Medicine of Jundiaí, Jundiaí, BrazilDepartment of Internal Medicine, Faculty of Medicine of Jundiaí, Jundiaí, BrazilDepartment of Internal Medicine, Faculty of Medicine of Jundiaí, Jundiaí, BrazilHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (USP), Institute of Psychiatry, Dr. Ovidio Pires de Campos, 785-1 Andar, Ala Sul, Sala Chefias Médicas, 05403-010 São Paulo, SP, BrazilDepartment of Internal Medicine, Faculty of Medicine of Jundiaí, Jundiaí, BrazilWe describe a case of severe psychotic disorder as the only manifestation of primary adrenal insufficiency. A 63-year-old man presented with psychotic symptoms without any prior psychiatric history. During the clinical and laboratorial investigation, exams revealed a normovolemic hyponatremia. The patient showed no other clinical signs or symptoms compatible with adrenal insufficiency but displayed very high ACTH and low serum cortisol concentrations. Brain magnetic resonance imaging showed no significant changes, including the pituitary gland. The patient was initially treated with intravenous corticosteroids, resulting in rapid remission of the psychotic symptoms. The association between adrenal insufficiency and neuropsychiatric symptoms is rare but these symptoms can often be the first clinical presentation of the disease.http://dx.doi.org/10.1155/2015/512430
spellingShingle Julia de Lima Farah
Carolina Villar Lauand
Lucas Chequi
Enrico Fortunato
Felipe Pasqualino
Luis Henrique Bignotto
Rafael Loch Batista
Ivan Aprahamian
Severe Psychotic Disorder as the Main Manifestation of Adrenal Insufficiency
Case Reports in Psychiatry
title Severe Psychotic Disorder as the Main Manifestation of Adrenal Insufficiency
title_full Severe Psychotic Disorder as the Main Manifestation of Adrenal Insufficiency
title_fullStr Severe Psychotic Disorder as the Main Manifestation of Adrenal Insufficiency
title_full_unstemmed Severe Psychotic Disorder as the Main Manifestation of Adrenal Insufficiency
title_short Severe Psychotic Disorder as the Main Manifestation of Adrenal Insufficiency
title_sort severe psychotic disorder as the main manifestation of adrenal insufficiency
url http://dx.doi.org/10.1155/2015/512430
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