SidF, a dual substrate N5-acetyl-N5-hydroxy-L-ornithine transacetylase involved in Aspergillus fumigatus siderophore biosynthesis
Siderophore-mediated iron acquisition is essential for the virulence of Aspergillus fumigatus, a fungus causing life-threatening aspergillosis. Drugs targeting the siderophore biosynthetic pathway could help improve disease management. The transacetylases SidF and SidL generate intermediates for dif...
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Main Authors: | Thanalai Poonsiri, Jan Stransky, Nicola Demitri, Hubertus Haas, Michele Cianci, Stefano Benini |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-06-01
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Series: | Journal of Structural Biology: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590152424000242 |
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