The dynamic immune behavior of primary and metastatic ovarian carcinoma

The dynamic immune behavior of primary and metastatic ovarian carcinoma

Abstract Patients with high-grade serous ovarian carcinoma (HGSC) are usually diagnosed with advanced-stage disease, and the tumors often have immunosuppressive characteristics. Together, these factors are important for disease progression, drug resistance, and mortality. In this study, we used a co...

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Main Authors: Elaine Stur, Fuduan Peng, Pang-ning Teng, Emine Bayraktar, Min Hu, Sara Corvigno, David J. Brown, Sanghoon Lee, Kathleen N. Moore, Nicholas W. Bateman, Kathleen M. Darcy, George L. Maxwell, Thomas P. Conrads, Nidhi Sahni, Ignacio Vázquez-García, Sohrab P. Shah, Joseph Celestino, Nicole D. Fleming, Nicholas E. Navin, Linghua Wang, Anil K. Sood
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00818-8
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