Interplay between tumor cells and immune cells of the colorectal cancer tumor microenvironment: Wnt/β-catenin pathway

Interplay between tumor cells and immune cells of the colorectal cancer tumor microenvironment: Wnt/β-catenin pathway

Colorectal cancer (CRC) is currently ranked as the third most frequent human cancer and the fourth leading cause of cancer-related deaths worldwide. Macrophages and immune cell subsets infiltrate the tumor microenvironment (TME) and modulate several cellular events and metabolic processes in CRC. Th...

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Bibliographic Details
Main Authors: Aisha Saleh Janeeh, Khuloud Bajbouj, Bilal Rah, Eman Abu-Gharbieh, Mawieh Hamad
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
Colorectal cancer
Wnt/β-catenin pathway
tumor microenvironment
macrophages
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1587950/full
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