Repellency Potential, Chemical Constituents of Ocimum Plant Essential Oils, and Their Headspace Volatiles against Anopheles gambiae s. s., Malaria Vector
African malaria mosquitoes (Anopheles gambiae sensu stricto) transmit a malaria parasite (Plasmodium falciparum) to humans. The current control strategies for the vector have mainly focussed on synthetic products, which negatively impact the environment and human health. Given the potential use of e...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2023/3848998 |
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| author | Jonathan Osei-Owusu William K. Heve Owusu Fordjour Aidoo Maxwell Jnr Opoku Joseph Apau Kodwo Ninsin Dadzie Bright Yaw Vigbedor Kwaafo Akoto Awuah-Mensah Margaret Appiah Akwasi Acheampong Michael Birkett Antony Hooper |
| author_facet | Jonathan Osei-Owusu William K. Heve Owusu Fordjour Aidoo Maxwell Jnr Opoku Joseph Apau Kodwo Ninsin Dadzie Bright Yaw Vigbedor Kwaafo Akoto Awuah-Mensah Margaret Appiah Akwasi Acheampong Michael Birkett Antony Hooper |
| author_sort | Jonathan Osei-Owusu |
| collection | DOAJ |
| description | African malaria mosquitoes (Anopheles gambiae sensu stricto) transmit a malaria parasite (Plasmodium falciparum) to humans. The current control strategies for the vector have mainly focussed on synthetic products, which negatively impact the environment and human health. Given the potential use of environmentally friendly plant-derived volatiles as a control, this work aims to examine and compare the repellency potential of essential oils and headspace volatiles from Ocimum gratissimum, Ocimum tenuiflorum, and Ocimum basilicum and their chemical compositions. The repellency potential and chemical composition of the plants were achieved by using the protected arm-in-cage method and gas chromatography-mass spectrometry (GC-MS) analysis. Among the three Ocimum species, both the essential oils and the headspace volatiles from O. tenuiflorum achieved the longest repellency time lengths of 90–120 minutes. One hundred and one (101) chemical constituents were identified in the headspace volatiles of the three Ocimum spp. Nonetheless, (−)-camphor, (E)-γ-bisabolene, terpinolene, β-chamigrene, cubedol, (E)-farnesol, germacrene D-4-ol, viridiflorol, γ-eudesmol, tetracyclo [6.3.2.0 (2,5).0(1,8)] tridecan-9-ol, 4,4-dimethyl, α-eudesmol, isolongifolol, and endo-borneol were unique only to O. tenuiflorum headspace volatiles. Either essential oils or headspace volatiles from O. tenuiflorum could offer longer protection time length to humans against An. gambiae. Though field studies are needed to assess the complementarity between the chemical constituents in the headspace volatiles of O. tenuiflorum, our observations provide a foundation for developing effective repellents against An. gambiae. |
| format | Article |
| id | doaj-art-24b1cbd989c443d7a4ccc0fa9c36cbef |
| institution | Kabale University |
| issn | 2090-9071 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-24b1cbd989c443d7a4ccc0fa9c36cbef2025-02-03T06:48:31ZengWileyJournal of Chemistry2090-90712023-01-01202310.1155/2023/3848998Repellency Potential, Chemical Constituents of Ocimum Plant Essential Oils, and Their Headspace Volatiles against Anopheles gambiae s. s., Malaria VectorJonathan Osei-Owusu0William K. Heve1Owusu Fordjour Aidoo2Maxwell Jnr Opoku3Joseph Apau4Kodwo Ninsin Dadzie5Bright Yaw Vigbedor6Kwaafo Akoto Awuah-Mensah7Margaret Appiah8Akwasi Acheampong9Michael Birkett10Antony Hooper11Department of Physical and Mathematical SciencesDepartment of Biological SciencesDepartment of Biological SciencesDepartment of Biological SciencesDepartment of ChemistryDepartment of Biological SciencesUniversity of Health and Allied SciencesDepartment of Physical and Mathematical SciencesDepartment of Environment and Public HealthDepartment of ChemistryChemical Ecology LaboratorySafety DepartmentAfrican malaria mosquitoes (Anopheles gambiae sensu stricto) transmit a malaria parasite (Plasmodium falciparum) to humans. The current control strategies for the vector have mainly focussed on synthetic products, which negatively impact the environment and human health. Given the potential use of environmentally friendly plant-derived volatiles as a control, this work aims to examine and compare the repellency potential of essential oils and headspace volatiles from Ocimum gratissimum, Ocimum tenuiflorum, and Ocimum basilicum and their chemical compositions. The repellency potential and chemical composition of the plants were achieved by using the protected arm-in-cage method and gas chromatography-mass spectrometry (GC-MS) analysis. Among the three Ocimum species, both the essential oils and the headspace volatiles from O. tenuiflorum achieved the longest repellency time lengths of 90–120 minutes. One hundred and one (101) chemical constituents were identified in the headspace volatiles of the three Ocimum spp. Nonetheless, (−)-camphor, (E)-γ-bisabolene, terpinolene, β-chamigrene, cubedol, (E)-farnesol, germacrene D-4-ol, viridiflorol, γ-eudesmol, tetracyclo [6.3.2.0 (2,5).0(1,8)] tridecan-9-ol, 4,4-dimethyl, α-eudesmol, isolongifolol, and endo-borneol were unique only to O. tenuiflorum headspace volatiles. Either essential oils or headspace volatiles from O. tenuiflorum could offer longer protection time length to humans against An. gambiae. Though field studies are needed to assess the complementarity between the chemical constituents in the headspace volatiles of O. tenuiflorum, our observations provide a foundation for developing effective repellents against An. gambiae.http://dx.doi.org/10.1155/2023/3848998 |
| spellingShingle | Jonathan Osei-Owusu William K. Heve Owusu Fordjour Aidoo Maxwell Jnr Opoku Joseph Apau Kodwo Ninsin Dadzie Bright Yaw Vigbedor Kwaafo Akoto Awuah-Mensah Margaret Appiah Akwasi Acheampong Michael Birkett Antony Hooper Repellency Potential, Chemical Constituents of Ocimum Plant Essential Oils, and Their Headspace Volatiles against Anopheles gambiae s. s., Malaria Vector Journal of Chemistry |
| title | Repellency Potential, Chemical Constituents of Ocimum Plant Essential Oils, and Their Headspace Volatiles against Anopheles gambiae s. s., Malaria Vector |
| title_full | Repellency Potential, Chemical Constituents of Ocimum Plant Essential Oils, and Their Headspace Volatiles against Anopheles gambiae s. s., Malaria Vector |
| title_fullStr | Repellency Potential, Chemical Constituents of Ocimum Plant Essential Oils, and Their Headspace Volatiles against Anopheles gambiae s. s., Malaria Vector |
| title_full_unstemmed | Repellency Potential, Chemical Constituents of Ocimum Plant Essential Oils, and Their Headspace Volatiles against Anopheles gambiae s. s., Malaria Vector |
| title_short | Repellency Potential, Chemical Constituents of Ocimum Plant Essential Oils, and Their Headspace Volatiles against Anopheles gambiae s. s., Malaria Vector |
| title_sort | repellency potential chemical constituents of ocimum plant essential oils and their headspace volatiles against anopheles gambiae s s malaria vector |
| url | http://dx.doi.org/10.1155/2023/3848998 |
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