Optimizing extracellular matrix for endothelial differentiation using a design of experiments approach
Abstract The extracellular matrix (ECM) plays a vital role in stem cell differentiation to endothelial cells in vivo and is also important for the specification of endothelial cells in vitro. Individual ECM components have previously been shown to support endothelial differentiation; here, we use a...
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| Main Authors: | Mikayla L. Hall, Wei-Han Lin, Brenda M. Ogle |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-09256-9 |
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