The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: A Review
Background. Patients with moderate-to-severe psoriasis are often treated with systemic immunosuppressant agents that decrease immune system function. For the elderly, these medications are often problematic due to their already immunosuppressed state and comorbidities. However, there are few studies...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Dermatology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2012/367475 |
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| _version_ | 1832563968079560704 |
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| author | Jillian W. Wong John Y. M. Koo |
| author_facet | Jillian W. Wong John Y. M. Koo |
| author_sort | Jillian W. Wong |
| collection | DOAJ |
| description | Background. Patients with moderate-to-severe psoriasis are often treated with systemic immunosuppressant agents that decrease immune system function. For the elderly, these medications are often problematic due to their already immunosuppressed state and comorbidities. However, there are few studies examining the effects of these medications on the elderly age group. Therefore, there is often discomfort among dermatologists treating elderly patients with psoriasis in utilizing systemic agents, frequently resulting in inadequate treatment. Objective. We review the safety profiles of systemic treatments often used to treat psoriasis and their possible adverse risks to the geriatric population. Methods. We conducted a search of PubMed’s Medline database of articles published from 2000 to 2011, which resulted in 14 articles. Conclusion. Treating geriatric patients with moderate-to-severe psoriasis remains a challenge due to immunosenescence and comorbidities. More studies focusing on psoriasis treatment safety in the geriatric population are needed. |
| format | Article |
| id | doaj-art-24a3ba70c56d41dea9ac1636bc1d4687 |
| institution | Kabale University |
| issn | 1687-6105 1687-6113 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Dermatology Research and Practice |
| spelling | doaj-art-24a3ba70c56d41dea9ac1636bc1d46872025-02-03T01:12:09ZengWileyDermatology Research and Practice1687-61051687-61132012-01-01201210.1155/2012/367475367475The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: A ReviewJillian W. Wong0John Y. M. Koo1University of Utah School of Medicine, Salt Lake City, UT 84132, USAPsoriasis and Skin Treatment Center, Department of Dermatology, University of California, San Francisco (UCSF), San Francisco, CA 94118, USABackground. Patients with moderate-to-severe psoriasis are often treated with systemic immunosuppressant agents that decrease immune system function. For the elderly, these medications are often problematic due to their already immunosuppressed state and comorbidities. However, there are few studies examining the effects of these medications on the elderly age group. Therefore, there is often discomfort among dermatologists treating elderly patients with psoriasis in utilizing systemic agents, frequently resulting in inadequate treatment. Objective. We review the safety profiles of systemic treatments often used to treat psoriasis and their possible adverse risks to the geriatric population. Methods. We conducted a search of PubMed’s Medline database of articles published from 2000 to 2011, which resulted in 14 articles. Conclusion. Treating geriatric patients with moderate-to-severe psoriasis remains a challenge due to immunosenescence and comorbidities. More studies focusing on psoriasis treatment safety in the geriatric population are needed.http://dx.doi.org/10.1155/2012/367475 |
| spellingShingle | Jillian W. Wong John Y. M. Koo The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: A Review Dermatology Research and Practice |
| title | The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: A Review |
| title_full | The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: A Review |
| title_fullStr | The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: A Review |
| title_full_unstemmed | The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: A Review |
| title_short | The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: A Review |
| title_sort | safety of systemic treatments that can be used for geriatric psoriasis patients a review |
| url | http://dx.doi.org/10.1155/2012/367475 |
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