Synthesis, Crystal Structure, and Biological Activity of cis/trans Amide Rotomers of (Z)-N′-(2-Oxoindolin-3-ylidene)formohydrazide
(Z)-N′-(2-Oxoindolin-3-ylidene)formohydrazide (2) was synthesized by the reaction of (Z)-3-hydrazonoindolin-2-one (1) with formic acid under reflux. The structure of 2 was characterized by IR, Mass, 1H NMR, and X-ray crystal structure determination. Interestingly, compound 2 appeared in DMSO-d6 as...
Saved in:
| Main Authors: | Hatem A. Abdel-Aziz, Hazem A. Ghabbour, Wagdy M. Eldehna, Maha M. Qabeel, Hoong-Kun Fun |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2014/760434 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Design, Synthesis, and Molecular Docking of 1-(1-(4-Chlorophenyl)-2-(phenylsulfonyl)ethylidene)-2-phenylhydrazine as Potent Nonazole Anticandidal Agent
by: Hazem A. Ghabbour, et al.
Published: (2014-01-01) -
5-Bromo-<i>N</i>′-(2-oxoindolin-3-ylidene)furan-2-carbohydrazide
by: Nur Pasca Aijijiyah, et al.
Published: (2024-12-01) -
Design and synthesis of antiproliferative 2-oxoindolin-3-ylidenes incorporating urea function with potential VEGFR-2 inhibitory properties
by: Dalia R. Aboshouk, et al.
Published: (2025-01-01) -
Synthesis of Dimethyl (<i>Z</i>)-((3-oxoindolin-2-ylidene) (aryl)methyl)phosphonates Through Tandem Cadogan and Arbuzov Reactions
by: Nicolai A. Aksenov, et al.
Published: (2025-05-01) -
Synthesis and Single Crystal X-Ray Structure of New (2E)-2-[3-(1H-Imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide
by: Mohamed I. Attia, et al.
Published: (2013-01-01)