Helicobacter pylori eradication and gastric cancer prevention in a pooled analysis of large-scale cohort studies in Japan

Helicobacter pylori eradication and gastric cancer prevention in a pooled analysis of large-scale cohort studies in Japan

Abstract Helicobacter pylori (H. pylori) infection is an established cause of gastric cancer. Although H. pylori eradication is suggested to decrease gastric cancer risk, this has not been fully investigated in general populations. This analysis included 48,530 Japanese men and women aged 40–74 year...

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Main Authors: Ayami Ono, Shiori Tanaka, Norie Sawada, Atsushi Goto, Shoichiro Tsugane, Isao Muraki, Kazumasa Yamagishi, Yu Sasaki, Yasuhiko Abe, Takamasa Kayama, Yoshiyuki Ueno, Eiko Saito, Taiki Yamaji, Motoki Iwasaki, Manami Inoue
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Gastric cancer
Helicobacter pylori
Atrophic gastritis
Eradication
Prospective cohort study
Japan
Online Access:https://doi.org/10.1038/s41598-025-00713-z
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