EVALUATION OF THE THERAPEUTIC EFFICACY OF HIGH-INTENSITY PULSED-PERIODIC LASER RADIATION (CLINICAL AND EXPERIMENTAL OBSERVATIONS)
From the experience of clinical observations, we have shown a high therapeutic effectiveness of the medical laser KULON-MED in: cosmetics, non-cancer inflammatory diseases of the gastrointestinal tract and cancer (cancer of the stomach and colon) as at different wavelengths, and with different types...
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| Format: | Article |
| Language: | Russian |
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QUASAR, LLC
2016-09-01
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| Series: | Исследования и практика в медицине |
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| Online Access: | https://www.rpmj.ru/rpmj/article/view/154 |
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| author | V. V. Sokolov A. D. Kaprin A. A. Pankratov N. M. Lepekhin Yu. S. Priseko V. G. Filippov M. V. Galyetov A. V. Khrapov |
| author_facet | V. V. Sokolov A. D. Kaprin A. A. Pankratov N. M. Lepekhin Yu. S. Priseko V. G. Filippov M. V. Galyetov A. V. Khrapov |
| author_sort | V. V. Sokolov |
| collection | DOAJ |
| description | From the experience of clinical observations, we have shown a high therapeutic effectiveness of the medical laser KULON-MED in: cosmetics, non-cancer inflammatory diseases of the gastrointestinal tract and cancer (cancer of the stomach and colon) as at different wavelengths, and with different types of photosensitizers. In the area of anti-tumor photodynamic therapy (PDT), based on experimental studies, we have showed the high antitumor (sarcoma S‑37) effectiveness of the laser (with the inhibition of tumor growth of up to 100%) for repetitively pulsed irradiation mode, and for mode fractionation doses laser radiation. In addition, significant differences are shown in the effectiveness of anticancer PDT methods in the application of high-intensity lasers, continuous and pulsed caused fundamental properties of laser radiation characteristics – time structure of the radiation pulses. Thus, for the first time we have shown that the time of high-intensity laser pulses structure significantly affects therapeutic efficacy laser system, and hence on the mechanisms of interaction of laser radiation with biological tissue. |
| format | Article |
| id | doaj-art-24871c08e46d4c3c93dbfbb84d192d44 |
| institution | DOAJ |
| issn | 2410-1893 |
| language | Russian |
| publishDate | 2016-09-01 |
| publisher | QUASAR, LLC |
| record_format | Article |
| series | Исследования и практика в медицине |
| spelling | doaj-art-24871c08e46d4c3c93dbfbb84d192d442025-08-20T03:22:00ZrusQUASAR, LLCИсследования и практика в медицине2410-18932016-09-0133839010.17709/2409-2231-2016-3-3-9118EVALUATION OF THE THERAPEUTIC EFFICACY OF HIGH-INTENSITY PULSED-PERIODIC LASER RADIATION (CLINICAL AND EXPERIMENTAL OBSERVATIONS)V. V. Sokolov0A. D. Kaprin1A. A. Pankratov2N. M. Lepekhin3Yu. S. Priseko4V. G. Filippov5M. V. Galyetov6A. V. Khrapov7P. Hertsen Moscow Oncology Research Institute – Branch of Nation al Medical Radiology Research Center, Ministry of Health of Russia; 3, 2nd Botkinskiy proezd, Moscow, 125284, RussiaP. Hertsen Moscow Oncology Research Institute – Branch of Nation al Medical Radiology Research Center, Ministry of Health of Russia; 3, 2nd Botkinskiy proezd, Moscow, 125284, RussiaP. Hertsen Moscow Oncology Research Institute – Branch of Nation al Medical Radiology Research Center, Ministry of Health of Russia; 3, 2nd Botkinskiy proezd, Moscow, 125284, RussiaResearch and Production Enterprise «VELIT»; 5, ul. Zavodskaya, Istra, 143500, RussiaResearch and Production Enterprise «VELIT»; 5, ul. Zavodskaya, Istra, 143500, RussiaResearch and Production Enterprise «VELIT»; 5, ul. Zavodskaya, Istra, 143500, RussiaResearch and Production Enterprise «VELIT»; 5, ul. Zavodskaya, Istra, 143500, RussiaResearch and Production Enterprise «VELIT»; 5, ul. Zavodskaya, Istra, 143500, RussiaFrom the experience of clinical observations, we have shown a high therapeutic effectiveness of the medical laser KULON-MED in: cosmetics, non-cancer inflammatory diseases of the gastrointestinal tract and cancer (cancer of the stomach and colon) as at different wavelengths, and with different types of photosensitizers. In the area of anti-tumor photodynamic therapy (PDT), based on experimental studies, we have showed the high antitumor (sarcoma S‑37) effectiveness of the laser (with the inhibition of tumor growth of up to 100%) for repetitively pulsed irradiation mode, and for mode fractionation doses laser radiation. In addition, significant differences are shown in the effectiveness of anticancer PDT methods in the application of high-intensity lasers, continuous and pulsed caused fundamental properties of laser radiation characteristics – time structure of the radiation pulses. Thus, for the first time we have shown that the time of high-intensity laser pulses structure significantly affects therapeutic efficacy laser system, and hence on the mechanisms of interaction of laser radiation with biological tissue.https://www.rpmj.ru/rpmj/article/view/154copper vapor laserthe time structure of radiation pulsessarcoma s-37 |
| spellingShingle | V. V. Sokolov A. D. Kaprin A. A. Pankratov N. M. Lepekhin Yu. S. Priseko V. G. Filippov M. V. Galyetov A. V. Khrapov EVALUATION OF THE THERAPEUTIC EFFICACY OF HIGH-INTENSITY PULSED-PERIODIC LASER RADIATION (CLINICAL AND EXPERIMENTAL OBSERVATIONS) Исследования и практика в медицине copper vapor laser the time structure of radiation pulses sarcoma s-37 |
| title | EVALUATION OF THE THERAPEUTIC EFFICACY OF HIGH-INTENSITY PULSED-PERIODIC LASER RADIATION (CLINICAL AND EXPERIMENTAL OBSERVATIONS) |
| title_full | EVALUATION OF THE THERAPEUTIC EFFICACY OF HIGH-INTENSITY PULSED-PERIODIC LASER RADIATION (CLINICAL AND EXPERIMENTAL OBSERVATIONS) |
| title_fullStr | EVALUATION OF THE THERAPEUTIC EFFICACY OF HIGH-INTENSITY PULSED-PERIODIC LASER RADIATION (CLINICAL AND EXPERIMENTAL OBSERVATIONS) |
| title_full_unstemmed | EVALUATION OF THE THERAPEUTIC EFFICACY OF HIGH-INTENSITY PULSED-PERIODIC LASER RADIATION (CLINICAL AND EXPERIMENTAL OBSERVATIONS) |
| title_short | EVALUATION OF THE THERAPEUTIC EFFICACY OF HIGH-INTENSITY PULSED-PERIODIC LASER RADIATION (CLINICAL AND EXPERIMENTAL OBSERVATIONS) |
| title_sort | evaluation of the therapeutic efficacy of high intensity pulsed periodic laser radiation clinical and experimental observations |
| topic | copper vapor laser the time structure of radiation pulses sarcoma s-37 |
| url | https://www.rpmj.ru/rpmj/article/view/154 |
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