WWP2 deletion aggravates acute kidney injury by targeting CDC20/autophagy axis

WWP2 deletion aggravates acute kidney injury by targeting CDC20/autophagy axis

Introduction: Acute kidney injury (AKI) is associated with high morbidity and mortality rates. The molecular mechanisms underlying AKI are currently being extensively investigated. WWP2 is an E3 ligase that regulates cell proliferation and differentiation. Whether WWP2 plays a regulatory role in AKI...

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Main Authors: Ran You, Yanwei Li, Yuteng Jiang, Dandan Hu, Menglei Gu, Wei Zhou, Shengnan Zhang, Mi Bai, Yunwen Yang, Yue Zhang, Songming Huang, Zhanjun Jia, Aihua Zhang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Advanced Research
Subjects:
WWP2
CDC20
Autophagy
Acute kidney injury
Tubular epithelial cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224002522
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