Identification of CCNB1 as a biomarker for cellular senescence in hepatocellular carcinoma: a bioinformatics and experimental validation study
Abstract Background Hepatocellular carcinoma (HCC), originating in the liver and often asymptomatic in early stages, frequently metastasises and recures post-surgery. Currently, reliable diagnostic biomarkers and therapeutic targets for HCC are lacking. This study investigates the influence of cellu...
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| Main Authors: | Zhilan Zhang, Jie Zhou, Ruiru Huang, Xingxing Zhuang, Shoudong Ni |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-03-01
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| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02182-2 |
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