Regularization by neural style transfer for MRI field-transfer reconstruction with limited data

Recent advances in MRI reconstruction have demonstrated remarkable success through deep learning-based models. However, most existing methods rely heavily on large-scale, task-specific datasets, making reconstruction in data-limited settings a critical yet underexplored challenge. While regularizati...

Full description

Saved in:
Bibliographic Details
Main Authors: Guoyao Shen, Yancheng Zhu, Mengyu Li, Ryan McNaughton, Hernan Jara, Sean B. Andersson, Chad W. Farris, Stephan Anderson, Xin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Artificial Intelligence
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/frai.2025.1579251/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850218699057790976
author Guoyao Shen
Guoyao Shen
Yancheng Zhu
Mengyu Li
Mengyu Li
Ryan McNaughton
Ryan McNaughton
Hernan Jara
Sean B. Andersson
Sean B. Andersson
Chad W. Farris
Stephan Anderson
Stephan Anderson
Xin Zhang
Xin Zhang
Xin Zhang
Xin Zhang
Xin Zhang
author_facet Guoyao Shen
Guoyao Shen
Yancheng Zhu
Mengyu Li
Mengyu Li
Ryan McNaughton
Ryan McNaughton
Hernan Jara
Sean B. Andersson
Sean B. Andersson
Chad W. Farris
Stephan Anderson
Stephan Anderson
Xin Zhang
Xin Zhang
Xin Zhang
Xin Zhang
Xin Zhang
author_sort Guoyao Shen
collection DOAJ
description Recent advances in MRI reconstruction have demonstrated remarkable success through deep learning-based models. However, most existing methods rely heavily on large-scale, task-specific datasets, making reconstruction in data-limited settings a critical yet underexplored challenge. While regularization by denoising (RED) leverages denoisers as priors for reconstruction, we propose Regularization by Neural Style Transfer (RNST), a novel framework that integrates a neural style transfer (NST) engine with a denoiser to enable magnetic field-transfer reconstruction. RNST generates high-field-quality images from low-field inputs without requiring paired training data, leveraging style priors to address limited-data settings. Our experiment results demonstrate RNST’s ability to reconstruct high-quality images across diverse anatomical planes (axial, coronal, sagittal) and noise levels, achieving superior clarity, contrast, and structural fidelity compared to lower-field references. Crucially, RNST maintains robustness even when style and content images lack exact alignment, broadening its applicability in clinical environments where precise reference matches are unavailable. By combining the strengths of NST and denoising, RNST offers a scalable, data-efficient solution for MRI field-transfer reconstruction, demonstrating significant potential for resource-limited settings.
format Article
id doaj-art-24778e50d53f4b7f9d2ad716dc6534bc
institution OA Journals
issn 2624-8212
language English
publishDate 2025-06-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Artificial Intelligence
spelling doaj-art-24778e50d53f4b7f9d2ad716dc6534bc2025-08-20T02:07:38ZengFrontiers Media S.A.Frontiers in Artificial Intelligence2624-82122025-06-01810.3389/frai.2025.15792511579251Regularization by neural style transfer for MRI field-transfer reconstruction with limited dataGuoyao Shen0Guoyao Shen1Yancheng Zhu2Mengyu Li3Mengyu Li4Ryan McNaughton5Ryan McNaughton6Hernan Jara7Sean B. Andersson8Sean B. Andersson9Chad W. Farris10Stephan Anderson11Stephan Anderson12Xin Zhang13Xin Zhang14Xin Zhang15Xin Zhang16Xin Zhang17Department of Mechanical Engineering, Boston University, Boston, MA, United StatesThe Photonics Center, Boston University, Boston, MA, United StatesDepartment of Mechanical Engineering, Boston University, Boston, MA, United StatesDepartment of Mechanical Engineering, Boston University, Boston, MA, United StatesThe Photonics Center, Boston University, Boston, MA, United StatesDepartment of Mechanical Engineering, Boston University, Boston, MA, United StatesThe Photonics Center, Boston University, Boston, MA, United StatesDepartment of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, United StatesDepartment of Mechanical Engineering, Boston University, Boston, MA, United StatesDivision of Systems Engineering, Boston University, Boston, MA, United StatesDepartment of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, United StatesThe Photonics Center, Boston University, Boston, MA, United StatesDepartment of Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, United StatesDepartment of Mechanical Engineering, Boston University, Boston, MA, United StatesThe Photonics Center, Boston University, Boston, MA, United StatesDepartment of Electrical and Computer Engineering, Boston University, Boston, MA, United StatesDepartment of Biomedical Engineering, Boston University, Boston, MA, United StatesDivision of Materials Science and Engineering, Boston University, Boston, MA, United StatesRecent advances in MRI reconstruction have demonstrated remarkable success through deep learning-based models. However, most existing methods rely heavily on large-scale, task-specific datasets, making reconstruction in data-limited settings a critical yet underexplored challenge. While regularization by denoising (RED) leverages denoisers as priors for reconstruction, we propose Regularization by Neural Style Transfer (RNST), a novel framework that integrates a neural style transfer (NST) engine with a denoiser to enable magnetic field-transfer reconstruction. RNST generates high-field-quality images from low-field inputs without requiring paired training data, leveraging style priors to address limited-data settings. Our experiment results demonstrate RNST’s ability to reconstruct high-quality images across diverse anatomical planes (axial, coronal, sagittal) and noise levels, achieving superior clarity, contrast, and structural fidelity compared to lower-field references. Crucially, RNST maintains robustness even when style and content images lack exact alignment, broadening its applicability in clinical environments where precise reference matches are unavailable. By combining the strengths of NST and denoising, RNST offers a scalable, data-efficient solution for MRI field-transfer reconstruction, demonstrating significant potential for resource-limited settings.https://www.frontiersin.org/articles/10.3389/frai.2025.1579251/fulldeep learningMRIimage reconstructionneural style transferregularization by denoising
spellingShingle Guoyao Shen
Guoyao Shen
Yancheng Zhu
Mengyu Li
Mengyu Li
Ryan McNaughton
Ryan McNaughton
Hernan Jara
Sean B. Andersson
Sean B. Andersson
Chad W. Farris
Stephan Anderson
Stephan Anderson
Xin Zhang
Xin Zhang
Xin Zhang
Xin Zhang
Xin Zhang
Regularization by neural style transfer for MRI field-transfer reconstruction with limited data
Frontiers in Artificial Intelligence
deep learning
MRI
image reconstruction
neural style transfer
regularization by denoising
title Regularization by neural style transfer for MRI field-transfer reconstruction with limited data
title_full Regularization by neural style transfer for MRI field-transfer reconstruction with limited data
title_fullStr Regularization by neural style transfer for MRI field-transfer reconstruction with limited data
title_full_unstemmed Regularization by neural style transfer for MRI field-transfer reconstruction with limited data
title_short Regularization by neural style transfer for MRI field-transfer reconstruction with limited data
title_sort regularization by neural style transfer for mri field transfer reconstruction with limited data
topic deep learning
MRI
image reconstruction
neural style transfer
regularization by denoising
url https://www.frontiersin.org/articles/10.3389/frai.2025.1579251/full
work_keys_str_mv AT guoyaoshen regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT guoyaoshen regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT yanchengzhu regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT mengyuli regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT mengyuli regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT ryanmcnaughton regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT ryanmcnaughton regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT hernanjara regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT seanbandersson regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT seanbandersson regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT chadwfarris regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT stephananderson regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT stephananderson regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT xinzhang regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT xinzhang regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT xinzhang regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT xinzhang regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata
AT xinzhang regularizationbyneuralstyletransferformrifieldtransferreconstructionwithlimiteddata