Dual-wavelength fluorescence study of <i>in vivo</i> accumulation and formation of 5-ALA-induced porphyrins

Dual-wavelength fluorescence study of <i>in vivo</i> accumulation and formation of 5-ALA-induced porphyrins

This article discusses the processes of 5-aminolevulinic acid (5-ALA) metabolism, as well as the accumulation and photobleaching of protoporphyrin IX (PpIX) during photodynamic therapy (PDT) of benign skin tumors using the application method of introducing a 20% 5-ALA solution. The exposure time of...

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Bibliographic Details
Main Authors: V. E. Zavedeeva, K. T. Efendiev, D. M. Kustov, L. Yu. Loschenova, V. B. Loschenov
Format: Article
Language:Russian
Published: Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" 2025-04-01
Series:Biomedical Photonics
Subjects:
spectral fluorescence diagnostics
photodynamic therapy
5-aminolevulinic acid
porphyrins
protoporphyrin ix
chlorin-type photoproducts
fluorescence spectra.
Online Access:https://www.pdt-journal.com/jour/article/view/697
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