MIRO1 Is Required for Dynamic Increases in Mitochondria-ER Contact Sites and Mitochondrial ATP During the Cell Cycle

MIRO1 Is Required for Dynamic Increases in Mitochondria-ER Contact Sites and Mitochondrial ATP During the Cell Cycle

Mitochondria-ER contact sites (MERCS) are vital for mitochondrial dynamics, lipid exchange, Ca<sup>2+</sup> homeostasis, and energy metabolism. We examined whether mitochondrial metabolism changes during the cell cycle depend on MERCS dynamics and are regulated by the outer mitochondrial...

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Bibliographic Details
Main Authors: Benney T. Endoni, Olha M. Koval, Chantal Allamargot, Tara Kortlever, Lan Qian, Riley J. Sadoski, Denise Juhr, Isabella M. Grumbach
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cells
Subjects:
mitochondria
ER
MERCS
MAM
MIRO1
cell cycle
Online Access:https://www.mdpi.com/2073-4409/14/7/482
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