BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts
Background: Inherited mutations in the tumour suppressor gene BRCA2 greatly increase the risk of developing breast, ovarian and other types of cancers. So far, most studies have focused on the role of BRCA-pathways in the maintenance of genomic stability.
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.3233/CLO-2009-0465 |
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| _version_ | 1832548384188137472 |
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| author | Asta Björk Jonsdottir Maaike P. G. Vreeswijk Ron Wolterbeek Peter Devilee Hans J. Tanke Jorunn E. Eyfjörd Karoly Szuhai |
| author_facet | Asta Björk Jonsdottir Maaike P. G. Vreeswijk Ron Wolterbeek Peter Devilee Hans J. Tanke Jorunn E. Eyfjörd Karoly Szuhai |
| author_sort | Asta Björk Jonsdottir |
| collection | DOAJ |
| description | Background: Inherited mutations in the tumour suppressor gene BRCA2 greatly increase the risk of developing breast, ovarian and other types of cancers. So far, most studies have focused on the role of BRCA-pathways in the maintenance of genomic stability. |
| format | Article |
| id | doaj-art-24655bd323a648ac8b0d4fef70a3706f |
| institution | Kabale University |
| issn | 1570-5870 1875-8606 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cellular Oncology |
| spelling | doaj-art-24655bd323a648ac8b0d4fef70a3706f2025-02-03T06:14:11ZengWileyCellular Oncology1570-58701875-86062009-01-0131319120110.3233/CLO-2009-0465BRCA2 Heterozygosity Delays Cytokinesis in Primary Human FibroblastsAsta Björk Jonsdottir0Maaike P. G. Vreeswijk1Ron Wolterbeek2Peter Devilee3Hans J. Tanke4Jorunn E. Eyfjörd5Karoly Szuhai6Faculty of Medicine, University of Iceland, Reykjavik, IcelandDepartment of Human Genetics, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Medical Statistics, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Human Genetics, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Molecular Cell Biology, Leiden University Medical Center, Leiden, The NetherlandsFaculty of Medicine, University of Iceland, Reykjavik, IcelandDepartment of Molecular Cell Biology, Leiden University Medical Center, Leiden, The NetherlandsBackground: Inherited mutations in the tumour suppressor gene BRCA2 greatly increase the risk of developing breast, ovarian and other types of cancers. So far, most studies have focused on the role of BRCA-pathways in the maintenance of genomic stability.http://dx.doi.org/10.3233/CLO-2009-0465 |
| spellingShingle | Asta Björk Jonsdottir Maaike P. G. Vreeswijk Ron Wolterbeek Peter Devilee Hans J. Tanke Jorunn E. Eyfjörd Karoly Szuhai BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts Cellular Oncology |
| title | BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts |
| title_full | BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts |
| title_fullStr | BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts |
| title_full_unstemmed | BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts |
| title_short | BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts |
| title_sort | brca2 heterozygosity delays cytokinesis in primary human fibroblasts |
| url | http://dx.doi.org/10.3233/CLO-2009-0465 |
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