Computer-aided drug design for the double-membrane vesicle pore complex inhibitors against SARS-CoV-2

Computer-aided drug design for the double-membrane vesicle pore complex inhibitors against SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of the ongoing global pandemic, has constituted the worst global health disaster in recent years. However, no antiviral drugs have proved clinically efficacious to combat SARS-CoV-2 infection. The SARS-CoV-2 double-m...

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Bibliographic Details
Main Authors: Wang Han, Ruiyuan Zhou, Ruolan Wang, Yanjun Dong, Zeeshan Muhammad, Bin Wang, Jianjun Geng, Haidong Wang, Wei Hou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Microbiology
Subjects:
SARS-CoV-2
double-membrane vesicle pore complex
computer-aided drug design
molecular docking
antiviral agents
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1562187/full
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